Serum IL-6 and IL-10 concentrations in bitches with pyometra undergoing ovariohysterectomy
Dąbrowski, Roman (University of Life Sciences in Lublin. Department and Clinic of Animal Reproduction)
Pastor Milán, Josep (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Szczubiał, Marek (University of Life Sciences in Lublin. Department and Clinic of Animal Reproduction)
Piech, Tomasz (University of Life Sciences in Lublin. Department and Clinic of Animal Reproduction)
Bochniarz, Mariola (University of Life Sciences in Lublin. Department and Clinic of Animal Reproduction)
Wawron, Władysław (University of Life Sciences in Lublin. Department and Clinic of Animal Reproduction)
Tvarijonaviciute, Asta (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)

Fecha:	2015
Resumen:	Pyometra is a serious bacterial infection of the uterus affecting female dogs and manifests as an accumulation of pus in the uterine lumen. The aim of the study was to assess changes in serum interleukin (IL)-6 and IL-10 concentrations in bitches with pyometra undergoing ovariohysterectomy. Blood samples were collected from healthy bitches (controls) and bitches with pyometra before surgery, and 3 and 10 days after ovariohysterectomy. Before surgery, bitches with pyometra had significantly higher serum concentrations of IL-6 and IL-10 than the controls. After surgery, the serum concentration of IL-6 and IL-10 decreased significantly. In healthy dogs, the concentration of IL-6 and IL-10 showed a significant increase 3 days after surgery followed by a decrease on day 10. An increase in serum concentrations of IL-6 and IL-10 was present before surgery in bitches with pyometra and 3 days after ovariohysterectomy in healthy controls. Concentrations decreased after ovariohysterectomy and/or proper healing, suggesting that these cytokines can be useful for assessment of the postoperative period in bitches.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Cytokines ; Bitches ; Pyometra ; Ovariohysterectomy ; Post surgery monitoring
Publicado en:	Acta Veterinaria Scandinavica, Vol. 57 (september 2015) , ISSN 1751-0147

DOI: 10.1186/s13028-015-0153-8
PMID: 26410584

4 p, 917.5 KB

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