Web of Science: 4 citas, Scopus: 4 citas, Google Scholar: citas
Serum haptoglobin dynamics in pigs vaccinated or not vaccinated against porcine circovirus type 2
Fraile, Lorenzo
Saco, Yolanda (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Grau-Roma, Llorenç
Nofrarías, Miquel (Fundació Centre de Recerca en Sanitat Animal)
López-Soria, Sergio (Fundació Centre de Recerca en Sanitat Animal)
Sibila, Marina (Fundació Centre de Recerca en Sanitat Animal)
Callén, Antonio
Bassols Teixidó, Anna Maria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Segalés, Joaquim (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)

Fecha: 2015
Resumen: The present work describes the serum haptoglobin (Hp) dynamics in piglets vaccinated and non-vaccinated with a commercial porcine circovirus type 2 (PCV2) vaccine at 3 weeks of age, and its relationship with the average daily weight gain (ADWG). The field study was carried out on two farms (A and B) with a previous clinical history of PCV2-systemic disease (PCV2-SD). The aim of the study was to assess whether Hp could be used as a surrogate marker of PCV2 vaccine efficacy. PCV2 infection was confirmed by quantitative real time PCR (qPCR) in pigs from both farms, but PCV2-SD was only diagnosed in farm A. No statistically significant relation was found between serum Hp concentration and the percentage of qPCR positive animals and the treatment applied (PCV2 vaccination) in both farms. On the other hand, using linear regression analysis, a significant negative correlation between the area under the curve of Hp (AUC) and ADWG was observed for farm A (p < 0. 00001) and B (p = 0. 01). Based on the obtained determination coefficient (R 2) values, AUC explained 20. 0 and 11. 6% of the observed ADWG for farms A and B, respectively. The present study supports that the measurement of acute phase proteins may be an indicator of ADWG in pig farms, but it was not apparently feasible to use the serum Hp concentration as a surrogate marker of PCV2 vaccine efficacy.
Derechos: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Lengua: Anglès.
Documento: article ; recerca ; publishedVersion
Materia: Acute phase proteins ; Average daily weight gain ; Porcine circovirus type 2-systemic disease (PCV2-SD) ; PCV2 inactivated vaccine
Publicado en: Porcine Health Management, Vol. 1 (april 2015) , ISSN 2055-5660

PMID: 28405412
DOI: 10.1186/2055-5660-1-3


4 p, 319.2 KB

El registro aparece en las colecciones:
Documentos de investigación > Documentos de los grupos de investigación de la UAB > Centros y grupos de investigación (producción científica) > Ciencias de la salud y biociencias > Centre de Recerca en Sanitat Animal (CReSA-IRTA)
Artículos > Artículos de investigación
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 Registro creado el 2018-01-31, última modificación el 2019-03-04



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