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Incidence of peripheral arterial disease in the ARTPER population cohort after 5 years of follow-up
Alzamora, Ma. Teresa (Institut Universitari d'Investigació en Atenció Primària (IDIAP Jordi Gol))
Forés, Rosa (Universitat Autònoma de Barcelona. Departament de Medicina)
Pera, Guillem (Research Unit Barcelonès Nord Maresme, ICS-IDIAP Jordi Gol)
Baena-Díez, José Miguel (Institut Català de la Salut. Centre d'Atenció Primària La Marina)
Heras, Antonio (Primary Healthcare Centre Riu Nord-Riu Sud, Institut Català de la Salut)
Sorribes, Marta (Primary Healthcare Centre Numància, Institut Català de la Salut)
Valverde, Marta (Universitat Autònoma de Barcelona. Departament de Medicina)
Muñoz, Laura (Research Unit Barcelonès Nord Maresme, ICS-IDIAP Jordi Gol)
Mundet-Tudurí, Xavier (Research Unit Barcelona, ICS-IDIAP Jordi Gol)
Torán, Pere (Research Unit Barcelonès Nord Maresme, ICS-IDIAP Jordi Gol)

Fecha: 2016
Resumen: To know the epidemiology (prevalence, incidence, progression and morbidity and mortality associated) of peripheral artery disease in general population and the factors associated with this progression is essential to know the evolution of atherosclerosis and develop preventive strategies. The aim of the study was to determine the incidence of PAD after 5 years of follow-up population-based cohort ARTPER, and the evolution of Ankle brachial Index (ABI) in this period. Peripheral artery disease incidence analysis after 5 years of follow-up of 3786 subjects > 50 years old. Peripheral artery disease incident when the second cross section Ankle brachial Index was <0. 9 in any of the lower limbs, with normal baseline (0. 9 to 1. 4). Between 2012 and 2013 2762 individuals (77 % participation) were re-examined. Finally analyzed 2256 subjects (after excluding pathological Ankle brachial Index) followed for 4. 9 years (range 3. 8 to 5. 8 years), totalling 11,106 person-years. Peripheral artery disease 95 new cases were detected, representing an incidence of 4. 3 % at 5 years and 8. 6 per 1000 person-years (95 % CI 6. 9 to 10. 5) being higher in men (10. 2, 95 % CI 7. 4 to 13. 5) than in women (7. 5, 95 % CI 5. 5 to 9. 9). Linear correlation between the baseline Ankle brachial Index and the second cross section was low (r = 0. 23). The incidence of peripheral artery disease in ARTPER cohort was 8. 6 cases per 1000 person-years, being higher in men, especially <65 years. The correlation between two measures Ankle brachial Index after 5 years of follow-up was low. One might consider whether Ankle brachial Index repeated measures could improve the correlation.
Derechos: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Lengua: Anglès
Documento: article ; recerca ; publishedVersion
Materia: Peripheral arterial disease ; Incidence ; Cardiovascular risk factors
Publicado en: BMC Cardiovascular disorders, Vol. 16 (january 2016) , ISSN 1471-2261

DOI: 10.1186/s12872-015-0170-6
PMID: 26758025


9 p, 672.6 KB

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