Cancer Salivary Biomarkers for Tumours Distant to the Oral Cavity
Rapado-González, Óscar (Department of Surgery and Surgical Medical Specialties, Medicine and Dentistry School, University of Santiago de Compostela, Santiago de Compostela 15782, Spain)
Majem Cavaller, Blanca (Hospital Universitari Vall d'Hebron)
Muinelo-Romay, Laura (Instituto de Investigación Sanitaria de Santiago (IDIS))
López-López, Rafa (Instituto de Investigación Sanitaria de Santiago (IDIS))
Suárez-Cunqueiro, María Mercedes (Department of Surgery and Surgical Medical Specialties, Medicine and Dentistry School, University of Santiago de Compostela, Santiago de Compostela 15782, Spain)
Universitat Autònoma de Barcelona

Date:	2016
Abstract:	The analysis of saliva as a diagnostic approach for systemic diseases was proposed just two decades ago, but recently great interest in the field has emerged because of its revolutionary potential as a liquid biopsy and its usefulness as a non-invasive sampling method. Multiple molecules isolated in saliva have been proposed as cancer biomarkers for diagnosis, prognosis, drug monitoring and pharmacogenetic studies. In this review, we focus on the current status of the salivary diagnostic biomarkers for different cancers distant to the oral cavity, noting their potential use in the clinic and their applicability in personalising cancer therapies.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Non-invasive diagnosis ; Saliva ; Systemic diseases ; Biomarkers ; Cancer
Published in:	International journal of molecular sciences, Vol. 17 (september 2016) , ISSN 1422-0067

DOI: 10.3390/ijms17091531
PMID: 27626410

18 p, 1.0 MB

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