The Gut Microbiome Profile in Obesity : A Systematic Review
Castañer, Olga (Institut Hospital del Mar d'Investigacions Mèdiques)
Goday Arnó, Albert (Universitat Autònoma de Barcelona. Departament de Medicina)
Park, Yong-Moon (National Institute of Environmental Health Sciences (Estats Units d'Amèrica))
Lee, Seung-Hwan (Division of Endocrinology & Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea)
Magkos, Faidon (Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore (NUS) and Clinical Nutrition Research Centre (CNRC), Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A ∗ STAR), Singapore)
Shiow, Sue-Anne Toh Ee (Regional Health System Planning and Development, Singapore)
Schröder, Helmut (Institut Hospital del Mar d'Investigacions Mèdiques)

Date:	2018
Abstract:	Gut microbiome has been identified in the past decade as an important factor involved in obesity, but the magnitude of its contribution to obesity and its related comorbidities is still uncertain. Among the vast quantity of factors attributed to obesity, environmental, dietary, lifestyle, genetic, and others, the microbiome has aroused curiosity, and the scientific community has published many original articles. Most of the studies related to microbiome and obesity have been reported based on the associations between microbiota and obesity, and the in-depth study of the mechanisms related has been studied mainly in rodents and exceptionally in humans. Due to the quantity and diverse information published, the need of reviews is mandatory to recapitulate the relevant achievements. In this systematic review, we provide an overview of the current evidence on the association between intestinal microbiota and obesity. Additionally, we analyze the effects of an extreme weight loss intervention such as bariatric surgery on gut microbiota. The review is divided into 2 sections: first, the association of obesity and related metabolic disorders with different gut microbiome profiles, including metagenomics studies, and second, changes on gut microbiome after an extreme weight loss intervention such as bariatric surgery.
Grants:	Instituto de Salud Carlos III JR14/0008 Instituto de Salud Carlos III JR17/00022
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article de revisió ; Article ; Versió publicada
Published in:	International Journal of Endocrinology, Vol. 2018 (march 2018) , ISSN 1687-8345

DOI: 10.1155/2018/4095789
PMID: 29849617

9 p, 690.6 KB

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