| Date: |
2018 |
| Description: |
27 p. |
| Abstract: |
Influenza virus type A is of great concern in human, domestic and wild animal health. The ability of this agent of moving from one species to another confirms the "one world" concept of influenza or "one flu". For this reason, the necessity of a "One Health" approach is required for the control and prevention of this disease. The establishment of certain guidelines and protocols for viral inactivation of Influenza virus would be highly advisable in terms of control and prevention of transmission. Ultraviolet radiation has been demonstrated to be an effective method to inactivate microorganisms through damage of their genome. This investigation wants to use the germicidal range of ultraviolet wavelength (UV-C) to determine the kinetic decay of influenza virus and at the same time to evaluate if there are any differences between four influenza type A strains from different origins (avian, swine and human) in terms of viral inactivation. The results showed that this method is effective to inactivate Influenza virus from different species. At the last time point (10 min. ), an inactivation of approximately half of the initial concentration of viruses was observed. The utility of this investigation is to translate these results of inactivation to more pathogenic viruses of the same family or of the same genome size, especially concerning the management of infectious sample in BSL-3 containment. |
| Rights: |
Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan aquestes es distribueixin sota la mateixa llicència que regula l'obra original i es reconegui l'autoria de l'obra original.  |
| Language: |
Anglès |
| Studies: |
Zoonosi i Una Sola Salut (One Health) [4315915] |
| Series: |
Facultat de Veterinària. Treballs de màster i postgrau. Màster Oficial - Zoonosi i Una Sola Salut (ONE HEALTH) |
| Document: |
Treball de fi de postgrau |
| Subject: |
Grip A (H1N1) ;
Virus de la grip ;
Aspectes immunològics |
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