COSMIC project : consensus on the objectives of the metabolic syndrome in clinic
Pedro-Botet, Juan (Universitat Autònoma de Barcelona. Departament de Medicina)
Ascaso, Juan F. (Instituto de Investigación Sanitaria INCLIVA (València, Comunitat Valenciana))
Barrios, Vivencio (Universidad Católica de Murcia. Departamento de Medicina)
De la Sierra, Alejandro (Universitat de Barcelona. Hospital Mútua de Terrassa)
Escalada, Javier (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición)
Millán, Jesús (Hospital General Universitario Gregorio Marañón)
Mostaza, Jose M. (Hospital Carlos III (Madrid))
Pérez-Martínez, Pablo (Hospital Universitario Reina Sofía (Còrdova, Espanya))
Pintó, Xavier (Hospital Universitari de Bellvitge)
Salas-Salvadó, Jordi (Hospital Universitari Sant Joan de Reus (Tarragona))
Valdivielso, Pedro (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia))

Date:	2018
Abstract:	Metabolic syndrome (MetS), a disorder with a high and growing prevalence, is a recognized risk factor for cardiovascular disease (CVD) and type 2 diabetes. It is a constellation of clinical and metabolic risk factors that include abdominal obesity, dyslipidemia, glucose intolerance, and hypertension. Unfortunately, MetS is typically underrecognized, and there is great heterogeneity in its management, which can hamper clinical decision-making and be a barrier to achieving the therapeutic goals of CVD and diabetes prevention. Although no single treatment for MetS as a whole currently exists, management should be targeted at treating the conditions contributing to it and possibly reversing the risk factors. All this justifies the need to develop recommendations that adapt existing knowledge to clinical practice in our healthcare system. In this regard, professionals from different scientific societies who are involved in the management of the different MetS components reviewed the available scientific evidence focused basically on therapeutic aspects of MetS and developed a consensus document to establish recommendations on therapeutic goals that facilitate their homogenization in clinical decision-making.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article de revisió ; Article ; Versió publicada
Subject:	Cardiovascular prevention ; Diabetes prevention ; Insulin resistance ; Hypertension ; Dyslipidemia ; Obesity
Published in:	Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol. 11 (october 2018) , p. 683-697, ISSN 1178-7007

DOI: 10.2147/DMSO.S165740
PMID: 30464566

15 p, 1.0 MB

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