Simultaneous Local Heating/Thermometry Based on Plasmonic Magnetochromic Nanoheaters
Li, Zhi (Institut Català de Nanociència i Nanotecnologia)
López-Ortega, Alberto (CIC nanoGUNE (Sant Sebastià, País Basc))
Aranda-Ramos, Antonio (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Tajada Herraiz, José Luis (Institut Català de Nanociència i Nanotecnologia)
Sort Viñas, Jordi (Universitat Autònoma de Barcelona. Departament de Física)
Nogués, Carme (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Vavassori, Paolo (CIC nanoGUNE (Sant Sebastià, País Basc))
Nogués, Josep (Institut Català de Nanociència i Nanotecnologia)
Sepúlveda, Borja (Institut Català de Nanociència i Nanotecnologia)

Additional title:	Simultaneous local nano-heating/thermometry based on plasmonic magnetochromic nanodomes
Date:	2018
Abstract:	A crucial challenge in nanotherapies is achieving accurate and real-time control of the therapeutic action, which is particularly relevant in local thermal therapies to minimize healthy tissue damage and necrotic cell deaths. Here, a nanoheater/thermometry concept is presented based on magnetoplasmonic (Co/Au or Fe/Au) nanodomes that merge exceptionally efficient plasmonic heating and simultaneous highly sensitive detection of the temperature variations. The temperature detection is based on precise optical monitoring of the magnetic-induced rotation of the nanodomes in solution. It is shown that the phase lag between the optical signal and the driving magnetic field can be used to detect viscosity variations around the nanodomes with unprecedented accuracy (detection limit 0. 0016 mPa s, i. e. , 60-fold smaller than state-of-the-art plasmonic nanorheometers). This feature is exploited to monitor the viscosity reduction induced by optical heating in real-time, even in highly inhomogeneous cell dispersions. The magnetochromic nanoheater/thermometers show higher optical stability, much higher heating efficiency and similar temperature detection limits (0. 05 °C) compared to state-of-the art luminescent nanothermometers. The technological interest is also boosted by the simpler and lower cost temperature detection system, and the cost effectiveness and scalability of the nanofabrication process, thereby highlighting the biomedical potential of this nanotechnology.
Grants:	Ministerio de Economía y Competitividad MAT2013-48628-R Ministerio de Economía y Competitividad MAT2016-77391-R Ministerio de Economía y Competitividad PCIN-2016-093 Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-292 Ministerio de Economía y Competitividad SEV-2013-0295 Ministerio de Economía y Competitividad FIS2015-64519-R Ministerio de Economía y Competitividad MDM-2016-0618 European Commission 648454
Rights:	Aquest material està protegit per drets d'autor i/o drets afins. Podeu utilitzar aquest material en funció del que permet la legislació de drets d'autor i drets afins d'aplicació al vostre cas. Per a d'altres usos heu d'obtenir permís del(s) titular(s) de drets.
Language:	Anglès
Document:	Article ; recerca ; Versió sotmesa a revisió
Subject:	Magnetoplasmonics ; Nanoheating ; Nanomagnetism ; Nanoplasmonics ; Nanothermometry ; Photothermal actuation
Published in:	Small (Weinheim), Vol. 14, Issue 24 (June 2018) , art. 1800868, ISSN 1613-6829

DOI: 10.1002/smll.201800868

Preprint 35 p, 2.8 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Group of Smart Nanoengineered Materials, Nanomechanics and Nanomagnetism (Gnm3) > SPIN-PORICS
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles