Adherence and satisfaction of smartphone- And smartwatch-based remote active testing and passive monitoring in people with multiple sclerosis : Nonrandomized interventional feasibility study
Midaglia, Luciana. (Universitat Autònoma de Barcelona. Departament de Medicina)
Mulero, P. (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Montalban, Xavier (University of Toronto)
Graves, Jennifer (University of California, San Diego. Department of Neurology)
Hauser, Stephen L. (Department of Neurology. University of California)
Julian, Laura (Genentech Inc)
Baker, Michael (F Hoffmann-La Roche Ltd)
Schadrack, Jan (F Hoffmann-La Roche Ltd)
Gossens, Christian (F Hoffmann-La Roche Ltd)
Scotland, Alf (F Hoffmann-La Roche Ltd)
Lipsmeier, Florian (F Hoffmann-La Roche Ltd)
Van Beek, Johan (F Hoffmann-La Roche Ltd)
Bernasconi, Corrado (F Hoffmann-La Roche Ltd)
Belachew, Shibeshih (F Hoffmann-La Roche Ltd)
Lindemann, Michael (Department of Economics. Baden-Wuerttemberg Cooperative State University)

Fecha:	2019
Resumen:	Background: Current clinical assessments of people with multiple sclerosis are episodic and may miss critical features of functional fluctuations between visits. Objective: The goal of the research was to assess the feasibility of remote active testing and passive monitoring using smartphones and smartwatch technology in people with multiple sclerosis with respect to adherence and satisfaction with the FLOODLIGHT test battery. Methods: People with multiple sclerosis (aged 20 to 57 years; Expanded Disability Status Scale 0-5. 5; n=76) and healthy controls (n=25) performed the FLOODLIGHT test battery, comprising active tests (daily, weekly, every two weeks, or on demand) and passive monitoring (sensor-based gait and mobility) for 24 weeks using a smartphone and smartwatch. The primary analysis assessed adherence (proportion of weeks with at least 3 days of completed testing and 4 hours per day passive monitoring) and questionnaire-based satisfaction. In-clinic assessments (clinical and magnetic resonance imaging) were performed. Results: People with multiple sclerosis showed 70% (16. 68/24 weeks) adherence to active tests and 79% (18. 89/24 weeks) to passive monitoring; satisfaction score was on average 73. 7 out of 100. Neither adherence nor satisfaction was associated with specific population characteristics. Test-battery assessments had an at least acceptable impact on daily activities in over 80% (61/72) of people with multiple sclerosis. Conclusions: People with multiple sclerosis were engaged and satisfied with the FLOODLIGHT test battery. FLOODLIGHT sensor-based measures may enable continuous assessment of multiple sclerosis disease in clinical trials and real-world settings.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Multiple sclerosis ; Patient adherence ; Patient satisfaction ; Smartphone ; Wearable electronic devices ; Mobile phone
Publicado en:	Journal of medical Internet research, Vol. 21 Núm. 8 (2019) , p. e14863, ISSN 1438-8871

DOI: 10.2196/14863
PMID: 31471961

15 p, 948.8 KB

El registro aparece en las colecciones:
Artículos > Artículos de investigación
Artículos > Artículos publicados