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| Home > Articles > Published articles > Sociodemographic changes and trends in the rates of new perinatal HIV diagnoses and transmission in Spain from 1997 to 2015 |
(Hospital Regional Universitario Carlos Haya (Málaga)) (Hospital Universitari Vall d'Hebron)| Date: | 2019 |
| Abstract: | Background There are not enough nationwide studies on perinatal HIV transmission in connection with a combination of antiretroviral treatments in Spain. Our objectives were to study sociodemographic changes and trends in the rates of HIV diagnoses and perinatal transmission in Spain from 1997 to 2015. Methods A retrospective study using data from Spanish Paediatric HIV Network (CoRISpe) and Spanish Minimum Basic Data Set (MDBS) was performed. HIV- diagnosed children between 1997 and 2015 were selected. Sociodemographic, clinical and immunovirological data of HIV-infected children and their mothers were studied in four calendar periods (P1: 1997-2000; P2: 2001-2005; P3: 2006-2010; P4: 2011-2015). Rates of perinatal HIV diagnoses and transmission from 1997 to 2015 were calculated. Results A total of 532 HIV-infected children were included in this study. Of these children, 406 were Spanish (76. 3%) and 126 immigrants (23. 7%). A decrease in the number of HIV diagnoses, 203 (38. 2%) children in the first (P1), 149 (28%) in the second (P2), 130 (24. 4%) in the third (P3) and 50 (9. 4%) in the fourth (P4) calendar periods was studied. The same decrease in the Spanish HIV-infected children (P1, 174 (46. 6%), P2, 115 (30. 8%), P3, 65 (17. 4%) and P4, 19 (5. 1%)) was monitored. However, an increase in the number of HIV diagnoses by sexual contact (P1: 0%; P2: 1. 3%; P3: 4. 6%; P4: 16%) was observed. The rates of new perinatal HIV diagnoses and perinatal transmission in Spanish children decreased from 0. 167 to 0. 005 per 100,000 inhabitants and 11. 4% to 0. 4% between 1997 and 2015, respectively. Conclusions A decline of perinatal HIV diagnoses and transmission was observed. However, an increase of teen-agers HIV diagnoses with sexual infection was studied. Public awareness campaigns directed to teen-agers are advisable to prevent HIV infection by sexual contact. |
| Grants: | Instituto de Salud Carlos III RD12-0017-0035 Instituto de Salud Carlos III RD12-0017-0037 Instituto de Salud Carlos III RD16-0025-0019 Instituto de Salud Carlos III RIS-EPICLIN-19-2015 Instituto de Salud Carlos III PI13-00422 Instituto de Salud Carlos III PI16-01863 Instituto de Salud Carlos III PT13-0010-0028 Instituto de Salud Carlos III PT17-0015-0042 |
| Rights: | Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.  |
| Language: | Anglès |
| Document: | Article ; recerca ; Versió publicada |
| Subject: | Female ; History, 21st Century ; HIV Infections ; Humans ; Infectious Disease Transmission, Vertical ; Male ; Pregnancy ; Public Health Surveillance ; Retrospective Studies ; Risk Factors ; Severity of Illness Index ; Spain |
| Published in: | PloS one, Vol. 14 Núm. 10 (2019) , p. e0223536, ISSN 1932-6203 |
