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Plasma iron concentrations and systemic inflammatory response syndrome in neonatal foals
Sanmartí, Júlia (Universitat Autònoma de Barcelona)
Armengou, Lara (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Viu, Judit (Hospital Veterinario Sierra de Madrid)
Alguacil, Eduardo (Uplands Way Vets Low Road)
Civit, Sandra (Ganaderia JM)
Ríos, José (Universitat Autònoma de Barcelona. Unitat de Bioestadística.)
José Cunilleras, Eduard (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)

Fecha: 2020
Resumen: Sparse information regarding plasma iron concentration in neonatal foals and its utility as an inflammatory marker in this population has been published. To determine the physiologic plasma iron concentration in neonatal foals. To assess its utility as an inflammatory marker to predict systemic inflammatory response syndrome (SIRS) and as a prognostic marker. Forty-seven ill neonatal foals admitted to a referral equine hospital were divided in 2 groups based on the SIRS criteria (24 SIRS and 23 non-SIRS). Two control groups of 43 hospital and 135 stud farm healthy neonatal foals were also included. Observational prospective study. Data were summarized by mean and its 95% confidence interval and absolute frequency and percentage for quantitative andqualitative variables. One-way ANOVA, ANCOVA (group and age effects) and Dunnett as posthoc analysis were used to compare plasma iron concentration among groups. Neonatal foals with SIRS did not have had any statistically significant different plasma iron concentrations compared to non-SIRS (P = . 56) and stud farm control group (P = . 99), 172. 8 μg/dL (95% CI; 126. 0-219. 6), 193. 1 μg/dL (139. 1-247. 2), and 181. 8 μg/dL (171. 3-192. 4), respectively. Plasma iron concentration had a large variability in healthy neonatal foals, and was negatively correlated with age in hospital controls (rho = −0. 387) and sick neonatal foals (rho = −0. 598) (P < . 001). Plasma iron was not a useful marker of SIRS in neonatal foals and was not associated with outcome.
Derechos: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Lengua: Anglès
Documento: article ; recerca ; publishedVersion
Materia: Critical care ; Monitoring ; Neonatal foals ; Plasma iron ; Systemic inflammatory response syndrome
Publicado en: Journal of Veterinary Internal Medicine, Vol. 34 (april 2020) , p. 1325-1331, ISSN 1939-1676

DOI: 10.1111/jvim.15770
PMID: 32297679


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