Prevalence of gastroesophageal reflux disease : a population-based cross-sectional study in southern Chile
Manterola, Carlos (Universidad de la Frontera, Chile)
Grande, L (Universitat Autònoma de Barcelona. Departament de Cirurgia)
Bustos Fernandez, Luis (Universidad de la Frontera, Chile)
Otzen, Tamara (Universidad de la Frontera, Chile)

Date:	2020
Abstract:	This study assessed the prevalence of gastroesophageal reflux disease (GERD) in a general adult population from Temuco in southern Chile. The association of GERD with demographic variables was also examined. A cross-sectional study among the general population of Temuco in southern Chile was conducted in 2017, using a validated and reliable questionnaire for detecting GERD. The urban area of Temuco, with a population of 245,317 inhabitants (2002 census), was divided into four zones, which were representative of the socioeconomic sectors of the city. The sample size was estimated assuming a prevalence of 52. 8%, an accuracy of 3. 0%, a confidence level of 95. 0%, and a design effect of 1. 15. Area sampling was used to build clusters. The prevalence of GERD was determined and associated factors were studied by means of bivariate and multivariate analyses. A total of 1,069 subjects (47. 9% women, median age 40 years) from the selected subareas were interviewed. The prevalence of GERD was 44. 8%. The most frequently reported symptom was regurgitation (54. 8%). One-third of subjects took medication to control symptoms and was considered 'sick' by the instrument, although >68% of them had never sought medical consultation. There was a significant association between GERD and age (P < 0. 001) and female gender (P = 0. 001). In this population-based study, the prevalence of GERD was high (44. 8%). GERD was associated with age and female gender.
Note:	Altres ajuts: Project MEC/80170022
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Gastroesophageal reflux disease ; Prevalence ; Cross-sectional studies ; Evidence-based medicine ; Clinical epidemiology
Published in:	Gastroenterology Report, Vol. 8 (february 2020) , p. 286-292, ISSN 2052-0034

DOI: 10.1093/gastro/goaa002
PMID: 32843975

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