Ancient and modern genomes unravel the evolutionary history of the rhinoceros family
Liu, Shanlin (China Agricultural University. Department of Entomology, College of Plant Protection)
Westbury, Michael V. (University of Copenhagen. The GLOBE Institute)
Dussex, Nicolas (Centre for Palaeogenetics)
Kieren, J. Mitchell (University of Adelaide. School of Biological Sciences)
Sinding, Mikkel-Holger S. (University of Copenhagen. The GLOBE Institute)
Heintzman, Peter D. (UiT The Arctic University of Norway. The Arctic University Museum of Norway)
Duchêne, David A. (University of Copenhagen. The GLOBE Institute)
Kapp, Joshua D. (University of California. Department of Ecology and Evolutionary Biology)
Von Seth, Joahanna (Centre for Palaeogenetics)
Heiniger, Holly (School of Biological Sciences, University of Adelaide)
Sánchez-Barreiro, Fátima (University of Copenhagen. The GLOBE Institute)
Margaryan, Ashot (University of Copenhagen. The GLOBE Institute)
André-Olsen, Remi (Stockholm University. Science for Life Laboratory)
De Cahsan, Binia (University of Copenhagen. The GLOBE Institute)
Meng, Guanliang (China National Genebank)
Yang, Chentao (China National Genebank)
Chen, Lei (Center for Ecological and Environmental Sciences)
Van der Valk, Tom (Uppsala University. Department of Cell and Molecular Biology)
Moodley, Yoshan (University of Venda. Department of Zoology)
Rookmaaker, Leendert (Rhino Resource Center)
Bruford, Michael W. (Cardiff University. School of Biosciences)
Ryder, Oliver A (San Diego Zoo Wildlife Alliance)
Steiner, Cynthia (San Diego Zoo Wildlife Alliance)
Bruins-van Sonsbeek, Linda G. R. (Rotterdam Zoo)
Vartanyan, Sergey (Russian Academy of Sciences)
Guo, Chunxue (China National Genebank)
Cooper, Alan (South Australian Museum)
Kosintsev, Pavel (Russian Academy of Sciences)
Kirillova, Irina (Russian Academy of Sciences)
Lister, Adrian M. (Natural History Museum)
Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont)
Gopalakrishnan, Shyam (University of Copenhagen. The GLOBE Institute)
Dunn, Robert R. (University of Copenhagen. The GLOBE Institute)
Lorenzen, Eline D. (University of Copenhagen. The GLOBE Institute)
Shapiro, Beth (University of California. Department of Ecology and Evolutionary Biology)
Zhang, Guojie (China National Genebank)
Antoine, Pierre-Olivier (Université Montpellier. Institut des Sciences de l'Évolution)
Dalén, Love (Centre for Palaeogenetics)
P. Gilbert, M. Thomas (University of Copenhagen. The GLOBE Institute)

Date:	2021
Abstract:	Only five species of the once-diverse Rhinocerotidae remain, making the reconstruction of their evolutionary history a challenge to biologists since Darwin. We sequenced genomes from five rhinoceros species (three extinct and two living), which we compared to existing data from the remaining three living species and a range of outgroups. We identify an early divergence between extant African and Eurasian lineages, resolving a key debate regarding the phylogeny of extant rhinoceroses. This early Miocene (∼16 million years ago [mya]) split post-dates the land bridge formation between the Afro-Arabian and Eurasian landmasses. Our analyses also show that while rhinoceros genomes in general exhibit low levels of genome-wide diversity, heterozygosity is lowest and inbreeding is highest in the modern species. These results suggest that while low genetic diversity is a long-term feature of the family, it has been particularly exacerbated recently, likely reflecting recent anthropogenic-driven population declines.
Grants:	European Commission 864203 European Commission 681396 Ministerio de Economía y Competitividad BFU2017-86471-P Ministerio de Ciencia e Innovación CEX2018-000792-M Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-880
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Rhinoceros ; Perissodactyl ; Conservation genomics ; Phylogenomics ; Genomic diversity
Published in:	Cell, Vol. 184 (September 2021) , p. 1-12, ISSN 1097-4172

DOI: 10.1016/j.cell.2021.07.032

1 p, 5.9 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Institut Català de Paleontologia Miquel Crusafont (ICP)
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