Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe : Current Evidence and EUROMENE Research Recommendations for Epidemiology
Estévez-López, Fernando (Erasmus MC University Medical Center)
Mudie, Kathleen (London School of Hygiene & Tropical Medicine)
Wang-Steverding, Xia (University of Warwick)
Bakken, Inger Johanne (Norwegian Institute of Public Health)
Ivanovs, Andrejs (Riga Stradins University)
Castro-Marrero, Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Nacul, Luis (London School of Hygiene & Tropical Medicine)
Alegre Martín, José (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Zalewski, Paweł (Nicolaus Copernicus University in Toruń)
Słomko, Joanna (Nicolaus Copernicus University in Toruń)
Strand, Elin Bolle (Oslo University Hospital (Oslo, Noruega))
Pheby, Derek (Buckinghamshire New University)
Shikova, Evelina (National Center of Infectious and Parasitic Diseases, Sofia)
Lorusso, Lorenzo (LASST-Lecco (Itàlia))
Capelli, Enrica (University of Pavia)
Sekulic, Slobodan (University of Novi Sad)
Scheibenbogen, Carmen (Charité - Universitätsmedizin Berlin)
Sepúlveda, Nuno (University of Lisbon)
Murovska, Modra (Riga Stradins University)
Lacerda, Eliana (London School of Hygiene & Tropical Medicine)
Universitat Autònoma de Barcelona

Date:	2020
Abstract:	This review aimed at determining the prevalence and incidence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in Europe. We conducted a primary search in Scopus, PubMed and Web of Science for publications between 1994 and 15 June 2019 (PROSPERO: CRD42017078688). Additionally, we performed a backward-(reference lists) and forward-(citations) search of the works included in this review. Grey literature was addressed by contacting all members of the European Network on ME/CFS (EUROMENE). Independent reviewers searched, screened and selected studies, extracted data and evaluated the methodological and reporting quality. For prevalence, two studies in adults and one study in adolescents were included. Prevalence ranged from 0. 1% to 2. 2%. Two studies also included incidence estimates. In conclusion, studies on the prevalence and incidence of ME/CFS in Europe were scarce. Our findings point to the pressing need for well-designed and statistically powered epidemiological studies. To overcome the shortcomings of the current state-of-the-art, EUROMENE recommends that future research is better conducted in the community, reviewing the clinical history of potential cases, obtaining additional objective information (when needed) and using adequate ME/CFS case definitions; namely, the Centers for Disease Control & Prevention−1994, Canadian Consensus Criteria, or Institute of Medicine criteria.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Central nervous system diseases ; Infections ; Muscular diseases ; Post-exertional malaise ; Virus diseases
Published in:	Journal of clinical medicine, Vol. 9 (may 2020) , ISSN 2077-0383

DOI: 10.3390/jcm9051557
PMID: 32455633

15 p, 708.0 KB

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