Patterns of Antibiotic Prescription in Colombia : Are There Differences between Capital Cities and Municipalities?
Machado-Alba, Jorge Enrique (Universidad Tecnológica de Pereira)
Valladales-Restrepo, Luis Fernando (Fundación Universitaria Autónoma de las Américas (Pereira, Colòmbia). Grupo de Investigación Biomedicina)
Gaviria-Mendoza, Andrés (Fundación Universitaria Autónoma de las Américas (Pereira, Colòmbia). Grupo de Investigación Biomedicina)
Machado-Duque, Manuel Enrique (Fundación Universitaria Autónoma de las Américas (Pereira, Colòmbia). Grupo de Investigación Biomedicina)
Figueras, Albert 1961- (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)

Fecha:	2020
Resumen:	The use of antibiotics is the most important modifiable risk factor for the development of microorganism resistance. A cross-sectional study of outpatients receiving antibiotic prescriptions registered in a population database in Colombia was conducted. The characteristics of the consumption in capital cities and small municipalities was studied and the AWaRe classification was used. AWaRe classifies antibiotics into three stewardship groups: Access, Watch and Reserve, to emphasize the importance of their optimal use and potential harms of antimicrobial resistance. A total of 182,397 patients were prescribed an antibiotic; the most common were penicillins (38. 6%), cephalosporins (30. 2%) and fluoroquinolones (10. 9%). 'Access' antibiotics (86. 4%) were the most frequently prescribed, followed by 'Watch' antibiotics (17. 0%). Being 18 or older, being male, living in a municipality, having one or more comorbidities and urinary, respiratory or gastrointestinal disorders increased the probability of receiving 'Watch' or 'Reserve' antibiotics. Penicillin and urinary antiseptic prescriptions predominated in cities, while cephalosporin and fluoroquinolone prescriptions predominated in municipalities. This analysis showed that the goal set by the WHO Access of mainly using Access antibiotics is being met, although the high use of Watch antibiotics in municipalities should be carefully studied to determine if it is necessary to design specific campaigns to improve antibiotics use.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Antibiotic prescription ; AWaRe classification ; Colombia ; Rural/urban consumption ; Fluoroquinolones ; Cephalosporins ; Drug utilization study
Publicado en:	Antibiotics, Vol. 9 (july 2020) , ISSN 2079-6382

DOI: 10.3390/antibiotics9070389
PMID: 32650491

14 p, 263.0 KB

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