Effects of neuro-adaptive electrostimulation therapy on pain and disability in fibromyalgia
Udina-Cortés, Carlos (Institute Neurolife)
Fernández-Carnero, Josué (Universidad Autónoma de Madrid)
Romano, Alberto Arribas (Universidad Rey Juan Carlos)
Cuenca-Zaldívar, Juan Nicolás (Universidad Francisco de Vitoria)
Villafañe, Jorge Hugo (IRCCS Fondazione Don Carlo Gnocchi)
Castro-Marrero, Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Alguacil-Diego, Isabel Maria (Universidad Rey Juan Carlos)
Universitat Autònoma de Barcelona

Fecha:	2020
Resumen:	To evaluate the effectiveness of non-invasive neuro-adaptive electrostimulation (NAE) therapy for treating chronic pain and disability in patients with fibromyalgia. A prospective, randomized, sham-controlled study was conducted in 37 women with fibromyalgia. Participants were randomly assigned to receive either active NAE (n = 20) or stimulation with a sham device (n = 17). Participants in the experimental arm received eight 30-minute sessions over 4 weeks (2 sessions per week). The sham group received eight 30-minute sessions of sham stimulation. Therapeutic effects on pain relief, disability, and quality of life were evaluated using outcome measures at baseline, at 4 weeks, and after 3 months' follow-up. The findings indicated a significant reduction of pain in the active NAE group compared with the sham group immediately post-intervention, with a difference on the Visual Analog Scale (VAS) of 3 points (P = . 001), and at 3 months' follow-up (P = . 02). There were significant intragroup differences between the groups (P < . 05) at post-intervention. After the intervention, both groups presented significant reductions on the Fibromyalgia Impact Questionnaire (FIQ) with respect to baseline (P = . 004), but not at the 3-month follow-up. In the conditioned pain modulation (CPM) in thumb variable we found significant differences between the groups at the 3-month follow-up (P = . 02). No additional benefits for conditioned pain modulation and disability were observed between groups at the 3-month follow-up. Furthermore, anxiety/depression and catastrophizing improved in both groups, but no differences between groups were found. In this fibromyalgia cohort, NAE therapy significantly improved pain and quality of life at 4 weeks, but not at 3-month follow-up, compared with the sham stimulation group. Future investigations are needed in larger populations to confirm these findings.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Electrostimulation ; Fibromyalgia ; Pain ; Rehabilitation
Publicado en:	Medicine, Vol. 99 (december 2020) , ISSN 1536-5964

DOI: 10.1097/MD.0000000000023785
PMID: 33371148

8 p, 361.4 KB

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