Neuropsychological Learning Deficits as Predictors of Treatment Outcome in Patients with Eating Disorders
Lucas, Ignacio (Hospital Universitari de Bellvitge)
Miranda-Olivos, Romina (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición)
Testa, Giulia (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición)
Granero, Roser (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut)
Sánchez, Isabel (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición)
Sánchez-González, Jessica (Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición)
Jiménez-Murcia, Susana (Universitat de Barcelona. Departament de Ciències Clíniques)
Fernández Aranda, Fernando (Universitat de Barcelona. Departament de Ciències Clíniques)

Fecha:	2021
Resumen:	Eating disorders (EDs) are severe psychiatric illnesses that require individualized treatments. Decision-making deficits have been associated with EDs. Decision-making learning deficits denote a lack of strategies to elaborate better decisions that can have an impact on recovery and response to treatment. This study used the Iowa Gambling Task (IGT) to investigate learning differences related to treatment outcome in EDs, comparing between patients with a good and bad treatment outcome and healthy controls. Likewise, the predictive role of impaired learning performance on therapy outcome was explored. Four hundred twenty-four participants (233 ED patients and 191 healthy controls) participated in this study. Decision making was assessed using the Iowa Gambling Task before any psychological treatment. All patients received psychological therapy, and treatment outcome was evaluated at discharge. Patients with bad outcome did not show progression in the decision-making task as opposed to those with good outcome and the healthy control sample. Additionally, learning performance in the decision-making task was predictive of their future outcome. The severity of learning deficits in decision making may serve as a predictor of the treatment. These results may provide a starting point of how decision-making learning deficits are operating as dispositional and motivational factors on responsiveness to treatment in EDs.
Ayudas:	Instituto de Salud Carlos III FISPI14/00290 Instituto de Salud Carlos III PI17/01167 Instituto de Salud Carlos III PI20/132 Generalitat de Catalunya. Departament de Salut SLT006/17/00246
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Eating disorders ; Decision making ; Learning ; Treatment outcome
Publicado en:	Nutrients, Vol. 13 (june 2021) , ISSN 2072-6643

DOI: 10.3390/nu13072145
PMID: 34201433

12 p, 1.1 MB

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