Web of Science: 12 citations, Scopus: 11 citations, Google Scholar: citations
Selection of Radiomics Features based on their Reproducibility
Ligero, Marta (Vall d'Hebron Institut d'Oncologia)
Torres, Guillermo (Universitat Autònoma de Barcelona. Departament de Ciències de la Computació)
Sánchez Ramos, Carles (Centre de Visió per Computador (Bellaterra, Catalunya))
Diaz-Chito, Katerine (Universitat Autònoma de Barcelona. Departament de Ciències de la Computació)
Pérez, Raquel (Vall d'Hebron Institut d'Oncologia)
Gil, Debora (Centre de Visió per Computador (Bellaterra, Catalunya))

Imprint: Institute of Electrical and Electronics Engineers (IEEE), cop. 2019
Description: 6 pag.
Abstract: Dimensionality reduction is key to alleviate machine learning artifacts in clinical applications with Small Sample Size (SSS) unbalanced datasets. Existing methods rely on either the probabilistic distribution of training data or the discriminant power of the reduced space, disregarding the impact of repeatability and uncertainty in features. In the present study is proposed the use of reproducibility of radiomics features to select features with high inter-class correlation coefficient (ICC). The reproducibility includes the variability introduced in the image acquisition, like medical scans acquisition parameters and convolution kernels, that affects intensity-based features and tumor annotations made by physicians, that influences morphological descriptors of the lesion. For the reproducibility of radiomics features three studies were conducted on cases collected at Vall Hebron Oncology Institute (VHIO) on responders to oncology treatment. The studies focused on the variability due to the convolution kernel, image acquisition parameters, and the inter-observer lesion identification. The features selected were those features with a ICC higher than 0. 7 in the three studies. The selected features based on reproducibility were evaluated for lesion malignancy classification using a different database. Results show better performance compared to several state-of-the-art methods including Principal Component Analysis (PCA), Kernel Discriminant Analysis via QR decomposition (KDAQR), LASSO, and an own built Convolutional Neural Network.
Grants: European Commission 712949
Ministerio de Economía, Industria y Competitividad FIS-G64384969
Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-1624
Rights: Tots els drets reservats.
Language: Anglès
Document: Capítol de llibre ; Versió acceptada per publicar
Subject: Feature Selection ; Reproducibility ; Radiomics
Published in: 2019 41st Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2019, p. 403-408, ISBN 978-1-5386-1311-5

DOI: 10.1109/EMBC.2019.8857879


7 p, 377.3 KB

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 Record created 2022-04-06, last modified 2023-02-28



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