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Influence of personality profile in patients with drug-resistant epilepsy on quality of life following surgical treatment : A 1-year follow-up study
Iurina, Elena (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Baillès, Eva (Hospital Nostra Senyora de Meritxell (Principat d'Andorra))
Carreño, Mar (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Donaire, Antonio (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Rumià, Jordi (Hospital Clínic i Provincial de Barcelona)
Boget-Llucià, Teresa (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Bargalló, Núria (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Setoain, Xavier (Hospital Clínic i Provincial de Barcelona)
Roldan, Pedro (Hospital Clínic i Provincial de Barcelona)
Conde-Blanco, Estefanía (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Centeno, Maria (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Pintor Pérez, Luis (Universitat de Barcelona. Departament de Medicina)

Date: 2022
Abstract: The objectives of this study are to determine the influence of personality profile in patients with drug-resistant epilepsy on quality of life (QoL) after surgical treatment and compare the results with a non-surgical control group at the 1-year follow-up. We conducted a prospective, comparative, controlled study, including 70 patients suffering from drug-resistant epilepsy. Demographic, psychiatric, neurological, and psychological data were recorded at the baseline and at the 1-year follow-up. Assessment of personality dimensions was performed using the NEO-FFI-R questionnaire; severity of anxiety and depression were assessed by the Hospital Anxiety and Depression Scale (HADS), and QoL was evaluated using the QOLIE-31. At the 1-year follow-up, comparing the control and the surgical groups, we detected differences in scores of most items of QoL, which were higher in those patients who had undergone surgery. High levels of Conscientiousness and Openness to experience at the baseline in patients who underwent surgery predicted better post-surgical outcomes in the QoL scores, whereas high neurotic patients showed worse QoL results. Postoperative changes in QoL in patients were associated with the personality profile at the baseline. QoL measures significantly improved in the surgical group compared with the non-surgical group but were not associated with baseline or postoperative seizure frequency at 1 year.
Note: Altres ajuts: acords transformatius de la UAB
Rights: Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original. Creative Commons
Language: Anglès
Document: Article ; recerca ; Versió publicada
Published in: Personality and Mental Health, 2022 , ISSN 1932-863X

DOI: 10.1002/pmh.1564


12 p, 651.7 KB

The record appears in these collections:
Articles > Research articles
Articles > Published articles

 Record created 2022-09-23, last modified 2023-12-15



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