Real-time genomics for One Health
Urban, Lara (Helmholtz Zentrum Muenchen)
Perlas Puente, Albert (Helmholtz Zentrum Muenchen)
Francino, Olga (Nano1Health, S.L.)
Martí-Carreras, Joan (Nano1Health, S.L.)
Muga, Brenda (University of Otago. Department of Anatomy)
Mwangi, Jenniffer W. (Machakos University. Biological Department)
Okalebo, Laura Boykin (BioTeam, Inc. (USA))
Stanton, Jo-Ann (University of Otago. Department of Anatomy)
Black, Amanda (Lincoln University. Bioprotection Aotearoa)
Waipara, Nick (Plant and Food Research (New Zealand))
Fontsere, Claudia (University of Copenhagen. The Globe Institute. Center for Evolutionary Hologenomics)
Eccles, David (Malaghan Institute of Medical Research. Hugh Green Cytometry Centre)
Urel, Harika (Helmholtz Zentrum Muenchen)
Reska, Tim (Helmholtz Zentrum Muenchen)
Morales, Hernan (University of Copenhagen. The Globe Institute. Center for Evolutionary Hologenomics)
Palmada-Flores, Marc (Institut de Biologia Evolutiva (UPF-CSIC) (Barcelona))
Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont)
Watsa, Mrinalini (San Diego Zoo Wildlife Alliance)
Libke, Zane (Instituto Nacional de Biodiversidad (Ecuador))
Erkenswick, Gideon (Field Projects International (USA))
van Oosterhout, Cock (University of East Anglia)

Date:	2023
Abstract:	The ongoing degradation of natural systems and other environmental changes has put our society at a crossroad with respect to our future relationship with our planet. While the concept of One Health describes how human health is inextricably linked with environmental health, many of these complex interdependencies are still not well-understood. Here, we describe how the advent of real-time genomic analyses can benefit One Health and how it can enable timely, in-depth ecosystem health assessments. We introduce nanopore sequencing as the only disruptive technology that currently allows for real-time genomic analyses and that is already being used worldwide to improve the accessibility and versatility of genomic sequencing. We showcase real-time genomic studies on zoonotic disease, food security, environmental microbiome, emerging pathogens, and their antimicrobial resistances, and on environmental health itself - from genomic resource creation for wildlife conservation to the monitoring of biodiversity, invasive species, and wildlife trafficking. We stress why equitable access to real-time genomics in the context of One Health will be paramount and discuss related practical, legal, and ethical limitations.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Global health ; Nanopore sequencing ; Nature conservation ; One Health ; Real-time genomics
Published in:	Molecular systems biology, Vol. 19, Issue 6 (June 2023) , art. e11686, ISSN 1744-4292

DOI: 10.15252/msb.202311686
PMID: 37325891

12 p, 1.3 MB

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Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Institut Català de Paleontologia Miquel Crusafont (ICP)
Articles > Research articles
Articles > Published articles