Trace cisplatin adsorption by thiol-functionalized sponge (TFS) and Sn/SnO2-coated TFS : Adsorption study and mechanism investigation
Han, Dong (Universitat Autònoma de Barcelona. Departament de Química)
Villanueva-Tagle, Margarita Edelia (Universidad de La Habana)
Peña-Icart, Mirella (Universidad de La Habana. Instituto de Ciencia y Tecnología de Materiales)
López-Mesas, Montserrat (Universitat Autònoma de Barcelona. Departament de Química)
Valiente Malmagro, Manuel (Universitat Autònoma de Barcelona. Departament de Química)

Date:	2024
Abstract:	To remove trace cisplatin from aqueous solution, commercial sponges were functionalized by esterification with 3-mercaptopropionic acid, followed by reduction with Na2S·9H2O or SnCl2·2H2O. The resulting thiol-functionalized sponges (TFSs), TFS_1 and TFS_2, were tested for the removal of cisplatin (235 μg L-1) achieving maximum removal of 95. 5 ± 0. 8% and 99. 5 ± 0. 1% respectively, which were significantly higher than the non-functionalized counterpart. The successful grafting of thiol groups, verified through FTIR, elemental analysis, SEM-EDS, and XPS characterization, facilitated Pt-S complexation during adsorption. The aqua-derivatives of cisplatin, formed through hydration, complexed with thiol sites through ligand displacement. Additionally, the presence of Sn/SnO2 coating on TFS_2 further enhanced the adsorption process. The rapid adsorption process conformed to pseudo-second-order kinetic model, involving both diffusion and chemisorption. While the Langmuir isotherm model generally described the monolayer adsorption behavior of cisplatin, the aggregation of Sn/SnO2 onto TFS_2 at 343 K introduced surface heterogeneity, rendering the Freundlich model a better fit for the adsorption isotherm. Differential pH dependence and the evaluation of mean free energy, derived from the Dubinin-Radushkevich isotherm model, indicated that cisplatin adsorption onto TFS_1 involved physisorption, including electrostatic attraction, while chemisorption predominated for TFS_2. Increasing the temperature notably promoted adsorption by facilitating the thermal-favored formation of Pt-S bonds.
Grants:	European Commission 778266
Note:	Altres ajuts: acords transformatius de la UAB
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Cisplatin ; Cytostatics ; Adsorption ; Functionalized materials ; Emerging pharmaceutical pollutants
Published in:	Journal of hazardous materials, Vol. 471 (June 2024) , art. 134442, ISSN 1873-3336

DOI: 10.1016/j.jhazmat.2024.134442
PMID: 38688222

12 p, 5.1 MB

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