Self-Degradable Photoactive Micromotors for Inactivation of Resistant Bacteria
Yuan, Xiaojiao (The Barcelona Institute of Science and Technology)
Suárez García, Salvio (Institut Català de Nanociència i Nanotecnologia)
De Corato, Marco (University of Zaragoza. Department of Science and Technology of Materials and Fluids)
Muñoz, Andrés Camilo (The Barcelona Institute of Science and Technology)
Pagonabarraga, Ignacio (Universitat de Barcelona. Departament de Física de la Matèria Condensada)
Ruiz-Molina, Daniel (Institut Català de Nanociència i Nanotecnologia)
Villa, K. (The Barcelona Institute of Science and Technology)

Date:	2024
Abstract:	Pathogenic bacteria pose a significant threat to human health, and their removal from food and water supplies is crucial in preventing the spread of waterborne and foodborne diseases. Recently, silver-based photocatalytic micromotors have emerged as promising candidates for inactivating pathogenic microbes due to their high antibacterial activity. In this study, the synthesis of photoactive AgPO micromotors with a well-defined tetrapod-like structure (TAMs) is presented using a simple precipitation method. These TAMs autonomously move and release Ag ions/nanoparticles (NPs) through a photodegradation process when exposed to light, which enhances their antimicrobial activity against Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacterial strains. Interestingly, different motion modes are observed under different manipulated light wavelengths and fuels. Furthermore, the self-degradation of TAMs is accelerated in the presence of negatively charged bacteria, which results in higher removal rates of both bacteria, E. Coli and S. aureus. The findings introduce a new concept of self-degradable micromotors based on photocatalytic components, which hold great potential for their use in antimicrobial applications. This work offers significant implications for materials chemistry, especially in designing and developing the next generation of light-driven antimicrobial agents.
Grants:	Agencia Estatal de Investigación PID2021-127983OB-C21 Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-673 European Commission 101076680 Agencia Estatal de Investigación RYC2021-031075-I Agencia Estatal de Investigación FJC2021-047222-I Agencia Estatal de Investigación CEX2021-001214-S Ministerio de Ciencia e Innovación RYC2021-030948-I
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Published in:	Advanced optical materials, Vol. 12, Issue 16 (June 2024) , art. 2303137, ISSN 2195-1071

DOI: 10.1002/adom.202303137

11 p, 3.8 MB

The record appears in these collections:
Research literature > UAB research groups literature > Research Centres and Groups (research output) > Experimental sciences > Catalan Institute of Nanoscience and Nanotechnology (ICN2)
Articles > Research articles
Articles > Published articles