Frequency of PCV-2 viremia in nursery piglets from a Spanish swine integration system in 2020 and 2022 considering PRRSV infection status
Sagrera, Mònica (Universitat Autònoma de Barcelona. Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal)
Garza-Moreno, Laura (Ceva Salud Animal)
Sibila Vidal, Rosa Marina (Universitat Autònoma de Barcelona. Unitat Mixta d'Investigació IRTA-UAB en Sanitat Animal)
Oliver-Ferrando, Salvador (Ceva Salud Animal)
Cárceles, Sonia (Ceva Salud Animal)
Casanovas, Carlos (Ceva Salud Animal)
Prieto, Patricia (Inga Food)
García-Flores, Alberto (Inga Food)
Espigares, David (Ceva Salud Animal)
Segalés Coma, Joaquim (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals)
Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals

Fecha:	2024
Resumen:	Background: Porcine circovirus 2 (PCV-2) poses a significant economic threat for the swine industry, causing a range of diseases collectively referred to as porcine circovirus diseases (PCVDs). Despite PCV-2 vaccine effectiveness, the need for monitoring infectious pressure remains. PCV-2 coinfection with other pathogens like porcine reproductive and respiratory syndrome virus (PRRSV) can exacerbate disease severity and lead to PCV-2-systemic disease cases. Monitoring both PRRSV and PCV-2 in co-infected farms is crucial for an effective management and vaccination programs. The present cross-sectional study aimed to determine PCV-2 antibody levels in piglets at weaning and PCV-2 and PRRSV viremia in pooled serum samples at weaning (vaccination age) and at 6 and 9 weeks of age from a Spanish swine integration system in 2020 (48 farms) and in 2022 (28 out of the 48 analysed previously). Results: The frequency of PCV-2 detection in pools of piglet sera was 2. 1% (2020) and 7. 1% (2022) at vaccination age but increased at the end of the nursery period (10. 4% in 2020 and 39. 3% in 2022) in both years. Co-infections between PCV-2 and PRRSV were detected in a significant proportion of PRRSV positive farms (15% in 2020, and 60% in 2022). PCV-2 antibody levels (ELISA S/P ratios) at weaning were lower in PCV-2 qPCR positive farms at different sampling time-points (0. 361 in 2020 and 0. 378 in 2022) compared to PCV-2 qPCR negative ones (0. 587 in 2020 and 0. 541 in 2022). The 28 farms tested both years were classified in four different epidemiological scenarios depending on their PCV-2 virological status. Those PCV-2 qPCR negative farms in 2020 that turned to be positive in 2022 had a statistically significant increase of PRRSV RT-qPCR detection and a PCV-2 antibody levels reduction, facts that were not observed in the rest of the scenarios. Conclusion: This epidemiological study in farms from the same integration system determined the occurrence, in 2020 and in 2022, of PCV-2 and PRRSV infections in piglets during the nursery period by using pooled serum samples.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Detection frequency ; Porcine circovirus 2 (PCV-2) ; Porcine reproductive and respiratory syndrome virus (PRRSV) ; Spain ; Viremia ; SDG 3 - Good Health and Well-being
Publicado en:	Porcine health management, Vol. 10 Núm. 1 (2024) , p. 4, ISSN 2055-5660

DOI: 10.1186/s40813-024-00354-0
PMID: 38229182

9 p, 1.1 MB

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