Multilayered Manufacturing Method for Microfluidic Systems Using Low-Cost, Resin-Based Three-Dimensional Printing
Manqueros-Avilés, Victor Edi (Instituto Tecnológico de la Laguna)
Coto-Fuentes, Hesner (Instituto Tecnológico de la Laguna)
Guevara-Amatón, Karla Victoria (Instituto Tecnológico de la Laguna)
Valdés-Perezgasga, Francisco (Instituto Tecnológico de la Laguna)
Alonso Chamarro, Julián (Universitat Autònoma de Barcelona. Departament de Química)

Date:	2025
Abstract:	This work presents a multilamination method for fabricating microfluidic devices or analytical microsystems using commercial 3D printers and photocurable resins as primary components. The developed method was validated by fabricating devices for the colorimetric measurement of copper ions in aqueous solutions, achieving results comparable to traditional cyclic olefin copolymer (COC) systems. The microfluidic platforms demonstrated stability and functionality over a twelve-week testing period. Channels with minimum dimensions of 0. 4 mm × 0. 4 mm were fabricated, and the feasibility of using resin modules for optical applications was demonstrated. This study highlights the potential of combining 3D printing with multilamination procedures as a versatile alternative, offering flexibility through the selection of a variety of available resins and commercial printers, as well as the ease of design development. This method offers significant reductions in cost, time, and manufacturing complexity by eliminating the need for equipment such as CNC machines, presses, and ovens, which are typically required in other multilamination technologies like LTCC and COC.
Grants:	Agencia Estatal de Investigación PID2020-117216RB-I00 Agència de Gestió d'Ajuts Universitaris i de Recerca 2021/SGR-00124
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Microfluidics ; Resin-based 3D printing ; Fabrication
Published in:	Sensors (Basel, Switzerland), Vol. 25, Issue 3 (February 2025) , art. 694, ISSN 1424-8220

DOI: 10.3390/s25030694
PMID: 39943333

13 p, 4.8 MB

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