Early Holocene preservation differences between cortical and trabecular bone proteomes
Ásmundsdóttir, Ragnheiður Diljá (University of Copenhagen. Faculty of Health and Medical Sciences)
Hansen, Jakob (Universitat Autònoma de Barcelona. Departament de Prehistòria)
Fagernäs, Zandra (University of Copenhagen. Faculty of Health and Medical Sciences)
Troché, Gaudry (University of Copenhagen. Faculty of Health and Medical Sciences)
Olsen, Jesper (University of Copenhagen. Faculty of Health and Medical Sciences)
Saña Seguí, Maria (Universitat Autònoma de Barcelona. Departament de Prehistòria)
Frido, Welker (University of Copenhagen. Faculty of Health and Medical Sciences)

Fecha:	2024
Descripción:	10 pàg.
Resumen:	Skeletal sample selection for evolutionary palaeoproteomic studies is currently based on the availability of material, without taking into account the influence of bone biology on the proteome composition of living bone. A prime example concerns the cortical and trabecular bone that is present simultaneously in many skeletal elements, including those recovered from archaeological sites. These two bone components are formed and maintained in different manners and at different rates. In palaeoproteomics there is currently no empirical data demonstrating differences in composition and/or preservation of cortical and trabecular bone proteomes. Here we analyse pairs of cortical and trabecular bone from six Early Holocene ungulate rib specimens from the site of La Draga, Spain, using shotgun proteomics. We observe generally larger proteomes, a larger number of peptides, and lower rates of degradation, for the cortical bone samples compared to the trabecular bone samples. These results suggest that in degraded proteomic contexts, preference should be given to the sampling of cortical bone in order to maximise the retrieval of larger and better-preserved bone proteomes.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, i la comunicació pública de l'obra, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. No es permet la creació d'obres derivades.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Palaeoproteomics ; Skeletal remains ; Osteogenesis ; Bone turnover ; Sampling ethics ; Shotgun proteomics ; ZooMS
Publicado en:	Journal of archaeological science: reports, Vol. 27 Núm. setembre (2024) , p. 104643, ISSN 2352-4103

DOI: 10.1016/j.jasrep.2024.104643

10 p, 2.1 MB

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