A field comparison study of two vaccine protocols against Erysipelothrix rhusiopathiae in two types of swine breeds in Spain
Sanchez-Tarifa, E. (University of Murcia)
Alonso, C. (Boehringer Ingelheim Vetmedica GmbH)
Perez, I. (Inga Food S.A.)
García, L. A. (Alvettia Gestión y Control S.L.)
Fernández-Fontelo, Amanda (Universitat Autònoma de Barcelona. Departament de Matemàtiques)
Gómez-Duran, O. (Boehringer Ingelheim Vetmedica GmbH)
García-Morante, B. (Centcinc)
García-Vázquez, Francisco A. (University of Murcia)
Hernández-Caravaca, I. (University of Alicante)

Fecha:	2024
Resumen:	Erysipelas still causes large economic losses to pig industry. Maternal immunity is critical to prevent erysipelas in young animals, thus, intensive vaccination protocols or practices focused on the improvement of the maternally derived immunity could provide substantial benefits. The present study evaluates potential changes in antibodies levels in sows and their offspring using two types of tests (commercial ELISA, Ingenasa or rSpaA415 ELISA) when two different vaccination programs (before farrowing or after farrowing) against Erysipelothrix rhusiopathiae were applied to sows from Iberian (A) or conventional Large White-Landrace (B) pig farms. The results showed a statistical correlation between titers found in sows and their one-week old piglets in both tests. The overall mean of (log) antibody titers in farm B measured by the commercial ELISA test was significantly higher in pre-farrowing vaccinated sows compared to the post-farrowing vaccine protocol (p = 0. 0278). Additionally, using the rSpaA415 ELISA test, the overall mean of (log) antibody titers was significantly higher in pre-farrowing sows (p = 0. 0056) compared to sows following post-farrowing vaccine protocol (p = 0. 0003) or non- vaccinated sows. None of the above-mentioned differences were found in farm A. The overall mean of (log) antibody titers in piglets from the pre-farrowing vaccination protocol was significantly higher than piglets from the post-farrowing vaccination protocol in farm A (p = 0. 0059; rSpaA415 ELISA) and farm B (p = 0. 0168 and p = 0. 0098 for the commercial and rSpaA415 ELISA data, respectively). Additionally, higher proportion of piglets from pre-farrowing vaccinated sows remained seropositive during the post-weaning period (days 42 to 84) compared to piglets from non-vaccinated or post-farrowing vaccinated groups in both farms A and B.
Derechos:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Lengua:	Anglès
Documento:	Article ; recerca ; Versió publicada
Materia:	Swine erisipelas ; Sow vaccination ; Maternally derived antibodies (MDA) ; ELISA
Publicado en:	BMC veterinary research, Vol. 20 (October 2024) , art. 461, ISSN 1746-6148

DOI: 10.1186/s12917-024-04065-0
PMID: 39394571

13 p, 5.6 MB

El registro aparece en las colecciones:
Artículos > Artículos de investigación
Artículos > Artículos publicados