Biodose Tools updates for criticality accidents and interlaboratory comparisons
Francès-Abellán, Anna (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
Endesfelder, David (Federal Office for Radiation Protection. Department of Effects and Risks of Lonising and Non-Ionising Radiation)
Hernández, Alfredo (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
Armengol, Gemma (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
Barquinero, Joan Francesc (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)

Fecha:	2026
Descripción:	13 pàg.
Resumen:	Purpose: Since its initial release, the aim of Biodose Tools was to offer an easy-to-use platform to perform the mathematical calculations needed in biological dosimetry. This update 3. 7. 1, mainly focuses on new features related to large-scale emergency responses, like criticality accidents dose estimation and laboratory networks. Material and Methods: Biodose Tools has been developed using the R programming language. The current version (3. 7. 1) uses the same external dependencies as version 3. 6. 1 (released November 2022) while integrating three new external packages to support the new functionalities. Results: Version 3. 7. 1 introduces different new modules: (a) a characteristic limits module that calculates decision thresholds and detection limits following ISO19238:2023 standards, and offers statistical tests to compare rates between suspected exposure cases and control data; (b) an enhanced dose estimation module which supports multiple dose assessments for dicentric and translocation assays for various exposure scenarios: acute, protracted, and highly protracted, as well as whole and partial-body exposures; (c) a criticality accidents module for multiple dose estimations using dicentrics in mixed gamma-neutron exposure scenarios (e. g. nuclear detonations); and (d) an Interlaboratory comparison module that automates the evaluation and comparison of dose estimates across laboratories. Conclusions: Biodose Tools (https://www. reneb. net/software/) continues to evolve in response to the dynamic needs of the biological dosimetry community, contributing to the preparedness and consistency in emergency response and routine applications.
Nota:	Altres ajuts: this work was supported by the Consejo de Seguridad Nuclear Español under Grant PR-102-2023.
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Lengua:	Anglès
Documento:	Article ; recerca ; Versió acceptada per publicar
Materia:	Biodose Tools update ; Biodosimetry ; Characteristic limits ; Criticality accidents ; Interlaboratory comparison
Publicado en:	International Journal of Radiation Biology, January 2026, ISSN 1362-3095

DOI: 10.1080/09553002.2026.2618524
PMID: 41569799

Disponible a partir de: 2027-12-30 44 p, 1.1 MB

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