Hepatitis E as a trigger for acute-on-chronic liver failure
Buti, Maria (Universitat Autònoma de Barcelona. Departament de Medicina)
Ruiz Cobo, Juan Carlos (Universitat Autònoma de Barcelona. Departament de Medicina)
Esteban, Rafael (Hospital Universitari Vall d'Hebron)
Riveiro Barciela, Mar (Universitat Autònoma de Barcelona. Departament de Medicina)

Date:	2024
Abstract:	Acute hepatitis E virus (HEV) infection is typically self-limiting and has a favourable prognosis. However, certain populations such as patients with pre-existing chronic liver disease may experience severe manifestations, including progression to acute-on-chronic liver failure (ACLF). Among viral hepatitis types, hepatitis A, E, and B are major causes of ACLF. Active screening and early diagnosis of HEV infection in patients with cirrhosis, especially those who develop ACLF, can improve management and enable timely antiviral therapy. Preventive measures, including HEV vaccination for high-risk groups, could reduce the morbidity and mortality associated with hepatitis E.
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	Hepatitis E ; Acute on chronic liver failure ; Liver cirrhosis ; Ribavirin ; Vaccination
Published in:	Clinical and Molecular Hepatology, Vol. 31 (November 2024) , p. S196-S204, ISSN 2287-285X

DOI: 10.3350/cmh.2024.0758
PMID: 39523715

10 p, 1.6 MB

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