Biodose Tools updates for criticality accidents and interlaboratory comparisons
Francès-Abellán, Anna (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
Endesfelder, David (German Federal Office For Radiation Protection)
Hernández, Alfredo
Armengol, Gemma (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)
Barquinero, Joan Francesc (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia)

Date:	2025
Abstract:	Purpose: Since its initial release, the aim of Biodose Tools was to offer an easy-to-use platform to perform the mathematical calculations needed in biological dosimetry. This update 3. 7. 1, mainly focuses on new features related to large-scale emergency responses, like criticality accidents dose estimation and laboratory networks. Material and Methods: Biodose Tools has been developed using the R programming language. The current version (3. 7. 1) uses the same external dependencies as version 3. 6. 1 (released November 2022) while integrating three new external packages to support the new functionalities. Results: Version 3. 7. 1 introduces different new modules: (a) a characteristic limits module that calculates decision thresholds and detection limits following ISO19238:2023 standards, and offers statistical tests to compare rates between suspected exposure cases and control data; (b) an enhanced dose estimation module which supports multiple dose assessments for dicentric and translocation assays for various exposure scenarios (acute, protracted, and highly protracted) as well as whole and partial-body exposures; (c) a criticality accidents module for multiple dose estimations using dicentrics in mixed gamma-neutron exposure scenarios (e. g. , nuclear detonations); and (d) an Interlaboratory comparison module that automates the evaluation and comparison of dose estimates across laboratories. Conclusions: Biodose Tools (this http URL) continues to evolve in response to the dynamic needs of the biological dosimetry community, contributing to the preparedness and consistency in emergency response and routine applications.
Note:	Altres ajuts: this work was supported by the Consejo de Seguridad Nuclear Español under Grant PR102-2023
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra, i la creació d'obres derivades, sempre que no sigui amb finalitats comercials i que es distribueixin sota la mateixa llicència que regula l'obra original. Cal que es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Prepublicació ; recerca ; Versió de l'autor

DOI: 10.48550/arXiv.2511.07497

Preprint 44 p, 1.1 MB

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