Sex differences in adults with attention-deficit/hyperactivity disorder : A population-based study
Mestres, Ferran (Hospital Universitari Vall d'Hebron)
Richarte, Vanesa (Universitat Autònoma de Barcelona)
Crespín, Juan Jesús (Vall d'Hebron Institut de Recerca (VHIR))
Torrent, Carla (Universitat de Barcelona)
Biel, Santiago (Hospital Universitari Vall d'Hebron)
Ramos, Carolina (Vall d'Hebron Institut de Recerca (VHIR))
Ibáñez, Pol (Vall d'Hebron Institut de Recerca (VHIR))
Oltra-Arañó, Laura (Hospital Universitari Vall d'Hebron)
Corrales, Montserrat (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Amoretti, Silvia (Instituto de Salud Carlos III)
Fadeuilhe, Christian (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)

Date:	2025
Abstract:	Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that often persists into adulthood, significantly impacting daily functioning and quality of life. Sex differences influence ADHD presentation, with females experiencing delayed diagnosis and distinct patterns of severity and comorbidities. Exploring these differences is essential for improving diagnostic accuracy and developing tailored interventions. This study examines ADHD severity, psychiatric comorbidities, and functional impairment by ADHD subtype and sex. This population-based study included 900 adults diagnosed with ADHD. ADHD severity, comorbidities, and functional outcomes were assessed using validated tools. Bivariate analyses and General Linear Models (GLMs) were applied to examine sex- and subtype-specific effects and their interactions. Females exhibited greater ADHD severity (p.
Grants:	Fundació la Marató de TV3 202234-32 Instituto de Salud Carlos III PI20/00344
Rights:	Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Language:	Anglès
Document:	Article ; recerca ; Versió publicada
Subject:	ADHD subtypes ; attention-deficit/hyperactivity disorder (ADHD) ; Functional impairment ; Psychiatric comorbidities ; Sex differences
Published in:	European psychiatry, Vol. 68 (April 2025) , art. e90, ISSN 1778-3585

DOI: 10.1192/j.eurpsy.2025.2441
PMID: 40211765

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