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Articles 27 records found  previous11 - 20next  jump to record: Search took 0.01 seconds. 
11.
9 p, 1.5 MB Decoding empagliflozin's molecular mechanism of action in heart failure with preserved ejection fraction using artificial intelligence / Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Iborra Egea, Oriol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Spitaleri, Giosafat (Universitat Autònoma de Barcelona. Departament de Medicina) ; Domingo, Mar (Universitat Autònoma de Barcelona. Departament de Medicina) ; Revuelta-López, Elena (Universitat Autònoma de Barcelona. Departament de Medicina) ; Codina, Pau (Universitat Autònoma de Barcelona. Departament de Medicina) ; Cediel, Germán (Universitat Autònoma de Barcelona. Departament de Medicina) ; Santiago Vacas, Evelyn (Universitat Autònoma de Barcelona. Departament de Medicina) ; Cserkóová, Adriana (Universitat Autònoma de Barcelona. Departament de Medicina) ; Pascual-Figal, Domingo (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ; Núñez, Julio (Hospital Clínic Universitari (València)) ; Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina)
The use of sodium-glucose co-transporter 2 inhibitors to treat heart failure with preserved ejection fraction (HFpEF) is under investigation in ongoing clinical trials, but the exact mechanism of action is unclear. [...]
2021 - 10.1038/s41598-021-91546-z
Scientific reports, Vol. 11 (june 2021)  
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12.
10 p, 744.9 KB Circulating neprilysin hypothesis : A new opportunity for sacubitril/valsartan in patients with heart failure and preserved ejection fraction? / Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ; Santiago Vacas, Evelyn (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cediel, Germán (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Codina, Pau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Domingo, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Revuelta-López, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Zamora, Elisabet (Universitat Autònoma de Barcelona. Departament de Medicina) ; Spitaleri, Giosafat (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Santesmases, Javier (Universitat Autònoma de Barcelona. Departament de Medicina) ; Núñez, Julio (Universitat de València. Departament de Medicina) ; Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Circulating Neprilysin (sNEP) has emerged as a potential prognostic biomarker in heart failure (HF). In PARAGON-HF benefit of sacubitril/valsartan was only observed in patients with left ventricular ejection fraction (LVEF) ≤57%. [...]
2021 - 10.1371/journal.pone.0249674
PloS one, Vol. 16 (may 2021)  
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13.
10 p, 672.1 KB Prognostic Value of New-Generation Troponins in -Segment-Elevation Myocardial Infarction in the Modern Era : The - Study / Cediel, Germán (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rueda, Ferran (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; García, Cosme (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Oliveras, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Labata, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Serra Flores, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Núñez, Julio (Universitat de València) ; Bodi, Vicente (Universitat de València) ; Ferrer Massot, Marc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Lupón, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
In -segment-elevation myocardial infarction (), troponins are not needed for diagnosis: symptoms and data are sufficient to activate percutaneous coronary intervention. This study explored the prognostic value of new-generation troponins in a real-life cohort contemporarily treated for . [...]
2017 - 10.1161/JAHA.117.007252
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 6, Num. 12 (december 2017)  
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14.
9 p, 1.2 MB Circulating miR-1254 predicts ventricular remodeling in patients with ST-Segment-Elevation Myocardial Infarction : A cardiovascular magnetic resonance study / Gonzalo Calvo, David de (Institut d'Investigació Biomèdica Sant Pau) ; Cediel, Germán (Universitat Autònoma de Barcelona. Departament de Medicina) ; Bär, Christian (Hannover Medical School. Institute of Molecular and Translational Therapeutic Strategies) ; Núñez, Julio (Hospital Clínic Universitari (València)) ; Revuelta-Lopez, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gavara Doñate, Jose (Universidad Politécnica de Madrid) ; Ríos-Navarro, César (Hospital Clínic Universitari (València)) ; Llorente-Cortes, Vicenta (Institut d'Investigació Biomèdica Sant Pau) ; Bodi, Vicente (Hospital Clínic Universitari (València)) ; Thum, Thomas (Imperial College London. National Heart and Lung Institute) ; Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Reliable noninvasive prognostic biomarkers for left ventricular (LV) remodeling in ST-segment elevation myocardial infarction (STEMI) are needed. This study aimed to evaluate a panel of circulating microRNAs (miRNAs) as biomarkers of LV remodeling using cardiovascular magnetic resonance (CMR). [...]
2018 - 10.1038/s41598-018-33491-y
Scientific reports, Vol. 8 (october 2018)  
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15.
13 p, 3.6 MB Circulating monocyte subsets and heart failure prognosis / Elchinova, Elena Georgieva (Universitat Autònoma de Barcelona. Departament de Medicina) ; Teubel, Iris (Institut Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Fernández, Marco A. (Institut Germans Trias i Pujol) ; Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; de Antonio Ferrer, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Moliner, Pedro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Domingo, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Zamora, Elisabet (Universitat Autònoma de Barcelona. Departament de Medicina) ; Núñez, Julio (Hospital Clínic Universitari (València)) ; Cediel, Germán (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Monocytes are a heterogeneous population of effector cells with key roles in tissue integrity restoration and maintenance. Here, we explore the association of monocyte subsets and prognosis in patients with ambulatory heart failure (HF). [...]
2018 - 10.1371/journal.pone.0204074
PloS one, Vol. 13 Núm. 9 (september 2018)  
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16.
10 p, 878.3 KB Predictive biomarkers for death and rehospitalization in comorbid frail elderly heart failure patients / Pacho Pacho, Cristina (Universitat Autònoma de Barcelona. Departament de Medicina) ; Domingo, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Núñez Aragón, Raquel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Lupón, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Núñez, Julio (Universitat de València. Departament de Medicina) ; Barallat, Jaume (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Moliner, Pedro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; de Antonio Ferrer, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Santesmases, Javier (Universitat Autònoma de Barcelona. Departament de Medicina) ; Cediel, Germán (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pastor, M. Cruz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Tor Aguilera, Jordi (Universitat Autònoma de Barcelona. Departament de Medicina) ; Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Heart failure (HF) is associated with a high rate of readmissions within 30 days post-discharge and in the following year, especially in frail elderly patients. Biomarker data are scarce in this high-risk population. [...]
2018 - 10.1186/s12877-018-0807-2
BMC geriatrics, Vol. 18 (may 2018)  
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17.
11 p, 922.2 KB Trends in Short- and Long-Term ST-Segment-Elevation Myocardial Infarction Prognosis Over 3 Decades : A Mediterranean Population-Based ST-Segment-Elevation Myocardial Infarction Registry / Garcia Garcia, Cosme (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Oliveras, Teresa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Serra Flores, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Vila, Joan (Institut Hospital del Mar d'Investigacions Mèdiques) ; Rueda, Ferran (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cediel, Germán (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Labata, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ferrer Massot, Marc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Carrillo, Xavier (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Degano, Irene R. (Institut Hospital del Mar d'Investigacions Mèdiques) ; De Diego, Oriol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; El Ouaddi, Nabil (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Montero, Santiago (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mauri, Josepa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Elosua, Roberto (Institut Hospital del Mar d'Investigacions Mèdiques) ; Lupón, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Coronary artery disease remains a major cause of death despite better outcomes of ST-segment-elevation myocardial infarction (STEMI). We aimed to analyze data from the Ruti-STEMI registry of in-hospital, 28-day, and 1-year events in patients with STEMI over the past 3 decades in Catalonia, Spain, to assess trends in STEMI prognosis. [...]
2020 - 10.1161/JAHA.120.017159
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 9 (october 2020)  
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18.
9 p, 1.4 MB Particle size and cholesterol content of circulating HDL correlate with cardiovascular death in chronic heart failure / Teis, Albert (Universitat Autònoma de Barcelona. Departament de Medicina) ; Cediel, Germán (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Amigó, Núria (Universitat Rovira i Virgili) ; Julve i Gil, Josep (Institut d'Investigació Biomèdica Sant Pau) ; Aranyó, Júlia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Andrés-Cordón, Joan Francesc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Puig-Jové, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Castelblanco, Esmeralda (Institut d'Investigació Biomèdica Sant Pau) ; Gual-Capllonch, Francesc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Ferrer-Sistach, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Vallejo Camazón, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Juncà Puig, Gladys (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; López-Ayerbe, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; de Antonio Ferrer, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Domingo, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Santiago Vacas, Evelyn (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Codina, Pau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mauricio Puente, Dídac (Universitat de Lleida) ; Lupón, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Alonso Pedrol, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Evidence regarding any association of HDL-particle (HDL-P) derangements and HDL-cholesterol content with cardiovascular (CV) death in chronic heart failure (HF) is lacking. To investigate the prognostic value of HDL-P size (HDL-Sz) and the number of cholesterol molecules per HDL-P for CV death in HF patients. [...]
2021 - 10.1038/s41598-021-82861-6
Scientific reports, Vol. 11 (february 2021)  
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19.
10 p, 1.1 MB Mortality trends in an ambulatory multidisciplinary heart failure unit from 2001 to 2018 / Spitaleri, Giosafat (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Lupón, Josep (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ; Domingo, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Santiago Vacas, Evelyn (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Codina, Pau (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Zamora, Elisabet (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ; Cediel, Germán (Universitat Autònoma de Barcelona. Departament de Medicina) ; Santesmases, Javier (Universitat Autònoma de Barcelona. Departament de Medicina) ; Diez-Quevedo, Crisanto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Troya, Maria Isabel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Boldo Alcaine, Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Altmir, Salvador (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Alonso Pedrol, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; González Fernández, Beatriz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Núñez, Julio (Universitat de València. Departament de Medicina) ; Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
To assess mortality trends at 1 and 3 years from 2001 to 2018 in a real-life cohort of HF outpatients from different etiologies with depressed and preserved LVEF. A total of 2368 consecutive patients with HF (mean age 66. [...]
2021 - 10.1038/s41598-020-79926-3
Scientific reports, Vol. 11 (january 2021)  
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20.
10 p, 4.3 MB Head-to-head comparison of contemporary heart failure risk scores / Codina, Pau (Universitat Autònoma de Barcelona. Departament de Medicina) ; Lupón, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Borrellas, Andrea (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Spitaleri, Giosafat (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cediel, Germán (Universitat Autònoma de Barcelona. Departament de Medicina) ; Domingo, Mar (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Simpson, Joanne (British Heart Foundation Cardiovascular Research Centre. University of Glasgow) ; Levy, Wayne C. (UW Medicine Heart Institute. University of Washington) ; Santiago Vacas, Evelyn (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Zamora, Elisabet (Universitat Autònoma de Barcelona. Departament de Medicina) ; Buchaca, David (Barcelona Supercomputing Center) ; Subirana, Isaac (Institut Hospital del Mar d'Investigacions Mèdiques) ; Santesmases, Javier (Universitat Autònoma de Barcelona. Departament de Medicina) ; Diez-Quevedo, Crisanto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Troya, Maria I. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Boldo Alcaine, Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Altmir, Salvador (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Alonso Pedrol, Núria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; González Fernández, Beatriz (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rivas Jiménez, Carmen (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Núñez, Julio (Universitat de València. Departament de Medicina) ; McMurray, John (British Heart Foundation Cardiovascular Research Centre. University of Glasgow) ; Bayés-Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Aims: Several heart failure (HF) web-based risk scores are currently used in clinical practice. Currently, we lack head-to-head comparison of the accuracy of risk scores. This study aimed to assess correlation and mortality prediction performance of Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC-HF) risk score, which includes clinical variables + medications; Seattle Heart Failure Model (SHFM), which includes clinical variables + treatments + analytes; PARADIGM Risk of Events and Death in the Contemporary Treatment of Heart Failure (PREDICT-HF) and Barcelona Bio-Heart Failure (BCN-Bio-HF) risk calculator, which also include biomarkers, like N-terminal pro B-type natriuretic peptide (NT-proBNP). [...]
2021 - 10.1002/ejhf.2352
European Journal of Heart Failure, Vol. 23 Núm. 12 (december 2021) , p. 2035-2044  
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