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Impact of Frailty on Mortality and Hospitalization in Chronic Heart Failure : A Systematic Review and Meta-Analysis / Yang, Xiaobo (Department of Medicine and Therapeutics Faculty of Medicine The Chinese University of Hong Kong Hong Kong) ; Lupón, Josep (Universitat Autònoma de Barcelona. Departament de Medicina) ; Vidán, Maria T. (Universidad Complutense de Madrid) ; Ferguson, Caleb (Western Sydney University and Western Sydney Local Health District) ; Gastelurrutia, Paloma (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Newton, Phillip J. (Western Sydney University and Western Sydney Local Health District) ; Macdonald, Peter S. (Heart and Lung Transplant Unit St Vincent's Hospital University of New South Wales Sydney) ; Bueno, Héctor (Hospital Universitario 12 de Octubre (Madrid)) ; Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Woo, Jean (The Chinese University of Hong Kong. CUHK Jockey Club Institute of Ageing) ; Fung, Erik (The Chinese University of Hong Kong)
Background: Although frailty has been associated with increased risks for hospitalization and mortality in chronic heart failure, the precise average effect remains uncertain. We performed a systematic review and meta-analysis to summarize the hazards for mortality and incident hospitalization in patients with heart failure and frailty compared with those without frailty and explored the heterogeneity underlying the effect size estimates. [...]
2018 - DOI (Digital Object Identifier)

10.1161/JAHA.117.008251
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol. 7 (december 2018)

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