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11 p, 4.9 MB Dynorphin A induces membrane permeabilization by formation of proteolipidic pores. Insights from electrophysiology and computational simulations / Perini, D. Aurora (Laboratory of Molecular Biophysics. Department of Physics. Universitat Jaume I) ; Aguilella-Arzo, Marcel (Laboratory of Molecular Biophysics. Department of Physics. Universitat Jaume I) ; Alcaraz, Antonio (Laboratory of Molecular Biophysics. Department of Physics. Universitat Jaume I) ; Perálvarez-Marín, Alex (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Queralt-Martín, María (Laboratory of Molecular Biophysics. Department of Physics. Universitat Jaume I)
Dynorphins are endogenous neuropeptides that function as ligands for the κ-opioid receptor. In addition to opioid activity, dynorphins can induce several pathological effects such as neurological dysfunctions and cell death. [...]
2021 - 10.1016/j.csbj.2021.12.021
Computational and Structural Biotechnology Journal, Vol. 20 (december 2021) , p. 230-240  

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