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Articles, 2 records found
Articles 2 records found  
1.
19 p, 600.4 KB Improvement in Parameters of Hematologic and Immunologic Function and Patient Well-being in the Phase III RESONATE Study of Ibrutinib Versus Ofatumumab in Patients With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma / Barrientos, Jacqueline C. (Zucker School of Medicine at Hofstra/Northwell) ; O'Brien, Susan (University of California Irvine) ; Brown, Jennifer R. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ; Kay, Neil E. (Mayo Clinic) ; Reddy, Nishitha M. (Vanderbilt-Ingram Cancer Center) ; Coutre, Steven E (Stanford University School of Medicine) ; Tam, Constantine (Peter MacCallum Cancer Centre and St Vincent's Hospital) ; Mulligan, Stephen (Royal North Shore Hospital) ; Jaeger, Ulrich (Medical University of Vienna) ; Devereux, Stephen (King's College Hospital NHS Foundation Trust) ; Pocock, Christopher (East Kent Hospitals University) ; Robak, Tadeusz (Medical University of Lodz) ; Schuster, Stephen J. (Perelman Center for Advanced Medicine) ; Schuh, Anna (University of Oxford) ; Gill, Devinder (Princess Alexandra Hospital) ; Bloor, Adrian (The Christie Clinic) ; Dearden, Claire (The Royal Marsden Hospital) ; Moreno, Carol (Institut d'Investigació Biomèdica Sant Pau) ; Cull, Gavin (Sir Charles Gardiner Hospital) ; Hamblin, Mike (Colchester Hospital) ; Jones, Jeffrey A. (The Ohio State University Comprehensive Cancer Center) ; Eckert, Karl (Pharmacyclics LLC. an AbbVie Company) ; Solman, Isabelle G. (Pharmacyclics LLC. an AbbVie Company) ; Suzuki, Samuel (Pharmacyclics LLC. an AbbVie Company) ; Hsu, Emily (Pharmacyclics LLC. an AbbVie Company) ; James, Danelle F. (Pharmacyclics LLC. an AbbVie Company) ; Byrd, John C. (The Ohio State University Comprehensive Cancer Center) ; Hillmen, Peter (The Leeds Teaching Hospitals. St. James University Hospital) ; Universitat Autònoma de Barcelona
In the phase III study RESONATE, ibrutinib reduced the risk of progression and improved overall survival versus ofatumumab in previously treated patients with CLL/SLL. In this novel analysis of patient well-being including patient-reported outcomes, ibrutinib reduced disease burden while preserving parameters of hematologic and immunologic function in RESONATE. [...]
2018 - 10.1016/j.clml.2018.08.007
Clinical Lymphoma, Myeloma & Leukemia, Vol. 18 Núm. 12 (december 2018) , p. 803-813.e7  
2.
12 p, 1.1 MB The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants / Rio-Machin, Ana (Queen Mary University of London) ; Vulliamy, Tom (Queen Mary University of London) ; Hug, Nele (University of Edinburgh) ; Walne, Amanda (Queen Mary University of London) ; Tawana, Kiran (Addenbrookes Hospital (Cambridge, Regne Unit)) ; Cardoso, Shirleny (Queen Mary University of London) ; Ellison, Alicia (Queen Mary University of London) ; Pontikos, Nikolas (Queen Mary University of London) ; Wang, Jun (Queen Mary University of London) ; Tummala, Hemanth (Queen Mary University of London) ; Al Seraihi, Ahad Fahad H. (Queen Mary University of London) ; Alnajar, Jenna (Queen Mary University of London) ; Bewicke-Copley, Findlay (Queen Mary University of London) ; Armes, Hannah (Queen Mary University of London) ; Barnett, Michael (University of British Columbia) ; Bloor, Adrian (Christie Hospital) ; Bödör, Csaba (Semmelweis University) ; Bowen, David (St James's University Hospital) ; Fenaux, Pierre (Université Paris) ; Green, Andrew (Our Lady's Children's Hospital) ; Hallahan, Andrew (Queensland Children's Hospital (Austràlia)) ; Hjorth-Hansen, Henrik (St Norwegian University of Science and Technology) ; Hossain, Upal (Barts NHS Trust) ; Killick, Sally (Royal Bournemouth General Hospital (Dorset, Regne Unit)) ; Lawson, Sarah (Birmingham Children's Hospital) ; Layton, Mark (Hammersmith Hospital (Londres)) ; Male, Alison M. (Great Ormond Street Hospital for Children (Londres)) ; Marsh, Judith (King's College Hospital NHS Foundation Trust) ; Mehta, Priyanka (University Hospitals Bristol NHS Foundation Trust) ; Mous, Rogier (Universitair Medisch Centrum Utrecht) ; Nomdedeu, Josep (Institut d'Investigació Biomèdica Sant Pau) ; Owen, Carolyn (Foothills Medical Centre) ; Pavlu, Jiri (Hammersmith Hospital (Londres)) ; Payne, Elspeth M. (University College London) ; Protheroe, Rachel E. (University Hospitals Bristol NHS Foundation Trust) ; Preudhomme, Claude (Universitaire de Lille. Jean-Pierre Aubert Research Center) ; Pujol-Moix, Nuria (Institut d'Investigació Biomèdica Sant Pau) ; Renneville, Aline (Broad Institute of MIT and Harvard) ; Russell, Nigel (Nottingham University Hospitals NHS Trust (Regne Unit)) ; Saggar, Anand (St George's Hospital Medical School) ; Sciuccati, Gabriela (Hospital de Pediatría "Prof. Dr. Juan P. Garrahan") ; Taussig, David (Royal Marsden Hospital (Regne Unit)) ; Toze, Cynthia L. (University of British Columbia) ; Uyttebroeck, Anne (University Hospitals Leuven (Bèlgica)) ; Vandenberghe, Peter (University Hospitals Leuven (Bèlgica)) ; Schlegelberger, Brigitte (Medizinische Hochschule Hannover) ; Ripperger, Tim (Medizinische Hochschule Hannover) ; Steinemann, Doris (Medizinische Hochschule Hannover) ; Wu, John (British Columbia Children's Hospital (Vancouver, Canadà)) ; Mason, Joanne (Birmingham Women's NHS Foundation Trust) ; Page, Paula (Birmingham Women's NHS Foundation Trust) ; Akiki, Susanna (Qatar Rehabilitation Institute) ; Reay, Kim (Birmingham Women's NHS Foundation Trust) ; Cavenagh, Jamie D. (Barts NHS Trust) ; Plagnol, Vincent (University College London) ; Caceres, Javier F. (University of Edinburgh) ; Fitzgibbon, Jude (Queen Mary University of London) ; Dokal, Inderjeet (Barts Health NHS Trust) ; Universitat Autònoma de Barcelona
The inclusion of familial myeloid malignancies as a separate disease entity in the revised WHO classification has renewed efforts to improve the recognition and management of this group of at risk individuals. [...]
2020 - 10.1038/s41467-020-14829-5
Nature communications, Vol. 11 (february 2020)  

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