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Resultados globales: 3 registros encontrados en 0.02 segundos.
Artículos, Encontrados 3 registros
Artículos Encontrados 3 registros  
1.
19 p, 600.4 KB Improvement in Parameters of Hematologic and Immunologic Function and Patient Well-being in the Phase III RESONATE Study of Ibrutinib Versus Ofatumumab in Patients With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma / Barrientos, Jacqueline C. (Zucker School of Medicine at Hofstra/Northwell) ; O'Brien, Susan (University of California Irvine) ; Brown, Jennifer R. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ; Kay, Neil E. (Mayo Clinic) ; Reddy, Nishitha M. (Vanderbilt-Ingram Cancer Center) ; Coutre, Steven E (Stanford University School of Medicine) ; Tam, Constantine (Peter MacCallum Cancer Centre and St Vincent's Hospital) ; Mulligan, Stephen (Royal North Shore Hospital) ; Jaeger, Ulrich (Medical University of Vienna) ; Devereux, Stephen (King's College Hospital NHS Foundation Trust) ; Pocock, Christopher (East Kent Hospitals University) ; Robak, Tadeusz (Medical University of Lodz) ; Schuster, Stephen J. (Perelman Center for Advanced Medicine) ; Schuh, Anna (University of Oxford) ; Gill, Devinder (Princess Alexandra Hospital) ; Bloor, Adrian (The Christie Clinic) ; Dearden, Claire (The Royal Marsden Hospital) ; Moreno, Carol (Institut d'Investigació Biomèdica Sant Pau) ; Cull, Gavin (Sir Charles Gardiner Hospital) ; Hamblin, Mike (Colchester Hospital) ; Jones, Jeffrey A. (The Ohio State University Comprehensive Cancer Center) ; Eckert, Karl (Pharmacyclics LLC. an AbbVie Company) ; Solman, Isabelle G. (Pharmacyclics LLC. an AbbVie Company) ; Suzuki, Samuel (Pharmacyclics LLC. an AbbVie Company) ; Hsu, Emily (Pharmacyclics LLC. an AbbVie Company) ; James, Danelle F. (Pharmacyclics LLC. an AbbVie Company) ; Byrd, John C. (The Ohio State University Comprehensive Cancer Center) ; Hillmen, Peter (The Leeds Teaching Hospitals. St. James University Hospital) ; Universitat Autònoma de Barcelona
In the phase III study RESONATE, ibrutinib reduced the risk of progression and improved overall survival versus ofatumumab in previously treated patients with CLL/SLL. In this novel analysis of patient well-being including patient-reported outcomes, ibrutinib reduced disease burden while preserving parameters of hematologic and immunologic function in RESONATE. [...]
2018 - 10.1016/j.clml.2018.08.007
Clinical Lymphoma, Myeloma & Leukemia, Vol. 18 Núm. 12 (december 2018) , p. 803-813.e7  
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2.
14 p, 1.1 MB Long-Term Studies Assessing Outcomes of Ibrutinib Therapy in Patients With Del(11q) Chronic Lymphocytic Leukemia / Kipps, Thomas J. (UC San Diego Moores Cancer Center) ; Fraser, Graeme (McMaster University (Canadà)) ; Coutre, Steven E (Stanford University School of Medicine) ; Brown, Jennifer R. (Dana-Farber Cancer Institute (Boston, Estats Units d'Amèrica)) ; Barrientos, Jacqueline C. (Northwell Health Cancer Institute) ; Barr, Paul M. (University of Rochester) ; Byrd, John C. (The Ohio State University Comprehensive Cancer Center) ; O'Brien, Susan M. (University of California) ; Dilhuydy, Marie-Sarah (Hôpital Haut-Lévêque) ; Hillmen, Peter (University of Leeds) ; Jaeger, Ulrich (Medical University of Vienna) ; Moreno, Carol (Institut d'Investigació Biomèdica Sant Pau) ; Cramer, Paula (University of Cologne) ; Stilgenbauer, Stephan (University of Ulm) ; Chanan-Khan, Asher A. (Mayo Clinic Cancer Center) ; Mahler, Michelle (Janssen Research and Development) ; Salman, Mariya (Janssen Research and Development) ; Eckert, Karl (Pharmacyclics LLC. an AbbVie Company) ; Solman, Isabelle G. (Pharmacyclics LLC. an AbbVie Company) ; Balasubramanian, Sriram (Janssen Research and Development) ; Cheng, Mei (Pharmacyclics LLC. an AbbVie Company) ; Londhe, Anil (Janssen Research and Development) ; Ninomoto, Joi (Pharmacyclics LLC. an AbbVie Company) ; Howes, Angela (Janssen Research and Development) ; James, Danelle F. (Pharmacyclics LLC. an AbbVie Company) ; Hallek, Michael (University of Cologne) ; Universitat Autònoma de Barcelona
Certain genomic features, such as del(11q), expression of unmutated immunoglobulin heavy-chain variable region (IGHV) gene, or complex karyotype, predict poorer outcomes to chemotherapy in patients with chronic lymphocytic leukemia (CLL). [...]
2019 - 10.1016/j.clml.2019.07.004
Clinical Lymphoma, Myeloma & Leukemia, Vol. 19 Núm. 11 (november 2019) , p. 715-722.e6  
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3.
13 p, 1.6 MB Resistance to PI3Kδ inhibitors in marginal zone lymphoma can be reverted by targeting the IL-6/PDGFRA axis / Arribas, Alberto J (SIB Swiss Institute of Bioinformatics) ; Napoli, Sara (Università della Svizzera Italiana) ; Cascione, Luciano (SIB Swiss Institute of Bioinformatics) ; Sartori, Giulio (Università della Svizzera Italiana) ; Barnabei, Laura (Università della Svizzera Italiana) ; Gaudio, Eugenio (Università della Svizzera Italiana) ; Tarantelli, Chiara (Università della Svizzera Italiana) ; Mensah, Afua Adjeiwaa (Università della Svizzera Italiana) ; Spriano, Filippo (Università della Svizzera Italiana) ; Zucchetto, Antonella (Centro di Riferimento Oncologico di Aviano) ; Rossi, Francesca M (Centro di Riferimento Oncologico di Aviano) ; Rinaldi, Andrea (Università della Svizzera Italiana) ; Castro de Moura, Manuel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Jovic, Sandra (Università della Svizzera italiana) ; Bordone-Pittau, Roberta (Oncology Institute of Southern Switzerland) ; Di Veroli, Alessandra (University of Perugia) ; Stathis, Anastasios (Università della Svizzera Italiana) ; Cruciani, Gabriele (University of Perugia) ; Stussi, Georg (Oncology Institute of Southern Switzerland) ; Gattei, Valter (Centro di Riferimento Oncologico di Aviano) ; Brown, Jennifer R (Harvard Medical School) ; Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Zucca, Emanuele (Oncology Institute of Southern Switzerland) ; Rossi, Davide (Oncology Institute of Southern Switzerland) ; Bertoni, Francesco (Oncology Institute of Southern Switzerland) ; Universitat Autònoma de Barcelona
PI3Kδ inhibitors are active in patients with lymphoid neoplasms and a first series of them have been approved for the treatment of multiple types of B-cell lymphoid tumors, including marginal zone lymphoma (MZL). [...]
2022 - 10.3324/haematol.2021.279957
Haematologica, Vol. 107 Núm. 11 (november 2022) , p. 2685-2697  
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