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4 p, 972.8 KB Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma : implications for biomarker-driven clinical trials / Montal, Robert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Andreu-Oller, Carmen (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Bassaganyas, Laia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Esteban-Fabró, Roger (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Moran, S (Institut d'Investigació Biomèdica de Bellvitge) ; Montironi, Carla (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Moeini, Agrin (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Pinyol, Roser (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Peix, Judit (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Cabellos, Laia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Villanueva, Augusto (Icahn School of Medicine at Mount Sinai) ; Sia, Daniela (Icahn School of Medicine at Mount Sinai) ; Mazzaferro, Vincenzo (University of Milan and Gastrointestinal Surgery and Liver Transplantation Unit. Fondazione IRCCS. Istituto Nazionale dei Tumori) ; Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Llovet, Josep M. (Institució Catalana de Recerca i Estudis Avançats) ; Universitat Autònoma de Barcelona
The clinical utility of serum alpha-fetoprotein (AFP) in patients with hepatocellular carcinoma (HCC) is widely recognised. However, a clear understanding of the mechanisms of AFP overexpression and the molecular traits of patients with AFP-high tumours are not known. [...]
2019 - 10.1038/s41416-019-0513-7
British Journal of Cancer, Vol. 121 Núm. 4 (13 2019) , p. 340-343  
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