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11 p, 2.5 MB Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis / Kandel, Prasanna (Department of Biochemistry and Molecular Biomedicine. Institute of Biomedicine. University of Barcelona) ; Semerci, Fatih (Universitat de Barcelona. Institut de Biomedicina. Departament de Bioquímica i Biomedicina Molecular) ; Mishra, Rachana (Jan and Dan Duncan Neurological Research Institute. Texas Children's Hospital) ; Choi, Willian (Medical Scientist Training Program. Baylor College of Medicine) ; Bajic, Aleksandar (Department of Molecular and Human Genetics. Baylor College of Medicine) ; Baluya, Dodge (Department of Interventional Radiology. University of Texas MD Anderson Cancer Center) ; Ma, Li Hua (NMR and Drug Metabolism Advanced Technology Cores. Baylor College of Medicine) ; Chen, Kevin (Department of Biosciences. Rice University) ; Cao, Austin C. (Department of Chemistry. Rice University) ; Phongmekhin, Tipwarin (Department of Biosciences. Rice University) ; Matinyan, Nick (Verna and Marrs McLean Department of Biochemistry and Molecular Biology. Baylor College of Medicine) ; Jimenez-Panizo, Alba (Universitat de Barcelona. Institut de Biomedicina. Departament de Bioquímica i Biomedicina Molecular) ; Chamakuri, Srinivas (Department of Pathology and Immunology. Baylor College of Medicine) ; Raji, Idris O. (Department of Pharmacology & Chemical Biology. Baylor College of Medicine) ; Chang, Lyra (Department of Pharmacology & Chemical Biology. Baylor College of Medicine) ; Fuentes-Prior, Pablo (Institut d'Investigació Biomèdica Sant Pau) ; MacKenzie, Kevin R. (Department of Molecular and Cellular Biology. Baylor College of Medicine) ; Benn, Caroline L. (Pfizer Regenerative Medicine) ; Estebanez-Perpiña, Eva (Department of Biochemistry and Molecular Biomedicine. Institute of Biomedicine. University of Barcelona) ; Venken, Koen (Verna and Marrs McLean Department of Biochemistry and Molecular Biology. Baylor College of Medicine) ; Moore, David D. (Department of Molecular and Cellular Biology. Baylor College of Medicine) ; Young, Damian W. (Center for Drug Discovery. Baylor College of Medicine) ; Maletic-Savatic, Mirjana (Department of Neuroscience. Baylor College of Medicine)
Neural stem cells, the source of newborn neurons in the adult hippocampus, are intimately involved in learning and memory, mood, and stress response. Despite considerable progress in understanding the biology of neural stem cells and neurogenesis, regulating the neural stem cell population precisely has remained elusive because we have lacked the specific targets to stimulate their proliferation and neurogenesis. [...]
2022 - 10.1073/pnas.2023784119
Proceedings of the National Academy of Sciences of the United States of America, Vol. 119 Núm. 13 (March 2022) , p. e2023784119  

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