Home > Search Results: Coras, Roxana
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Results overview: Found 5 records in 0.03 seconds.
Articles, 4 records found
Research literature, 1 records found
Articles 4 records found  
1.
10 p, 2.3 MB Synovial tissue metabolomic profiling reveal biomarkers of synovial inflammation in patients with osteoarthritis / Murillo-Saich, Jessica D. (University of California. Department of Medicine) ; Coras, Roxana (Universitat Autònoma de Barcelona. Departament de Medicina) ; Meyer, Robert (San Diego VA Healthcare Service) ; Llorente, Cristina (University of California. Department of Medicine) ; Lane, Nancy E. (University of California. Department of Medicine) ; Guma, Monica 1971- (San Diego VA Healthcare Service)
Inflammatory responses are associated with changes in tissue metabolism. Prior studies find altered metabolomic profiles in both the synovial fluid (SF) and serum of osteoarthritis subjects. Our study determined the metabolomic profile of synovial tissue (ST) and SF of individuals with osteoarthritis (OA) and its association with synovial inflammation. [...]
2022 - 10.1016/j.ocarto.2022.100295
Osteoarthritis and Cartilage Open, Vol. 4 (july 2022)  
Detailed record - Creative Commons
2.
11 p, 2.9 MB Serum metabolomic profiling predicts synovial gene expression in rheumatoid arthritis / Narasimhan, Rekha (University of California) ; Coras, Roxana (Universitat Autònoma de Barcelona. Departament de Medicina) ; Rosenthal, Sara B. (University of California) ; Sweeney, Shannon R. (University of Texas at Austin. Department of Nutritional Sciences & Dell Pediatric Research Institute) ; Lodi, Alessia (University of Texas at Austin. Department of Nutritional Sciences & Dell Pediatric Research Institute) ; Tiziani, Stefano (University of Texas at Austin. Department of Nutritional Sciences & Dell Pediatric Research Institute) ; Boyle, David (University of California. Division of Rheumatology) ; Kavanaugh, Arthur (University of California) ; Guma, Monica 1971- (Universitat Autònoma de Barcelona. Departament de Medicina)
Metabolomics is an emerging field of biomedical research that may offer a better understanding of the mechanisms of underlying conditions including inflammatory arthritis. Perturbations caused by inflamed synovial tissue can lead to correlated changes in concentrations of certain metabolites in the synovium and thereby function as potential biomarkers in blood. [...]
2018 - 10.1186/s13075-018-1655-3
Arthritis research & therapy, Vol. 20 (august 2018)  
Detailed record - Creative Commons
3.
13 p, 2.0 MB Differences in oxylipin profile in psoriasis versus psoriatic arthritis / Coras, Roxana (Universitat Autònoma de Barcelona) ; Kavanaugh, Arthur (University of California San Diego. Department of Medicine) ; Kluzniak, Angela (University of Rochester. Department of Medicine) ; Holt, Dustina (University of Rochester. Department of Medicine) ; Weilgosz, Amy (University of Rochester. Department of Medicine) ; Aaron, Armando (University of California San Diego. Department of Pharmacology) ; Quehenberger, Oswald (University of California San Diego. Department of Pharmacology) ; Ritchlin, Christopher (University of Rochester. Department of Medicine) ; Guma, Monica 1971- (Universitat Autònoma de Barcelona)
Oxylipins are biological lipids that have been implicated in inflammation. We previously found that certain oxylipins correlated with clinical manifestations in psoriatic arthritis (PsA) patients. Here, we compare oxylipin profiles in PsA patients and those with psoriasis (PsO) without inflammatory arthritis to identify oxylipins that associate with specific disease manifestations to better understand disease pathogenesis and identify new biomarkers. [...]
2021 - 10.1186/s13075-021-02575-y
Arthritis research & therapy, Vol. 23 (july 2021)  
Detailed record - Creative Commons
4.
7 p, 567.5 KB Design of an anti-inflammatory diet (ITIS diet) for patients with rheumatoid arthritis / Bustamante, Marta F. (Department of Medicine, University of California San Diego, San Diego, CA, USA) ; Agustín Perez, Meritxall (Department of Medicine, University of California San Diego, San Diego, CA, USA) ; Cedola, Francesca (Department of Medicine, University of California San Diego, San Diego, CA, USA) ; Coras, Roxana (Universitat Autònoma de Barcelona. Departament de Medicina) ; Narasimhan, Rekha (Department of Medicine, University of California San Diego, San Diego, CA, USA) ; Golshan, Shahrokh (Department of Psychiatry, University of California San Diego, San Diego, CA, USA) ; Guma, Monica 1971- (Universitat Autònoma de Barcelona. Departament de Medicina)
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability. Although recent pharmaceutical advances have improved treatment of RA, patients with RA often inquire about dietary interventions to improve RA symptoms, as they perceive rapid changes in their symptoms after consumption of certain foods. [...]
2020 - 10.1016/j.conctc.2020.100524
Contemporary Clinical Trials Communications, Vol. 17 (january 2020)  
Detailed record - Creative Commons

Research literature 1 records found  
1.
225 p, 14.2 MB Identification of Metabolites as Biomarkers and Mediators of Inflammation in Inflammatory Arthritis / Coras, Roxana ; Guma, Monica, 1971-, dir. ; Marsal Barril, Sara, dir. ; Selva O'Callaghan, Albert, dir.
L'artritis inflamatòria representa una gran càrrega social i econòmica tot i els recents avenços terapèutics. Malgrat un millor coneixement dels mecanismes patogénics, l'elecció de l'tractament encara es realitza a manera de prova, el que condueix a una manca de control de l'activitat de la malaltia en aproximadament el 30% dels pacients i una alta taxa d'efectes secundaris. [...]
La artritis inflamatoria representa una gran carga social y económica a pesar de los recientes avances terapéuticos. A pesar de un mejor conocimiento de los mecanismos patogénicos, la elección del tratamiento todavía se realiza a modo de prueba, lo que conduce a una falta de control de la actividad de la enfermedad en aproximadamente el 30 % de los pacientes y una alta tasa de efectos secundarios. [...]
Inflammatory arthritis represents a great social and economic burden despite recent therapeutic advances. Although we have a better understanding of the pathogenic mechanisms, treatment election is still made on a trial basis, which leads to lack of control of disease activity in approximately 30% of patients and a high rate of side effects. [...]
2021  
Detailed record - Creative Commons

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