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10 p, 790.0 KB Assessment of the End Point Adjudication Process on the Results of the Platelet-Oriented Inhibition in New TIA and Minor Ischemic Stroke (POINT) Trial : A Secondary Analysis / Farrant, Mary (University of California) ; Easton, J.Donald (University of California) ; Adelman, Eric E. (University of Wisconsin) ; Cucchiara, Brett L. (University of Pennsylvania) ; Barsan, Willian G. (University of Michigan) ; Tillman, Holly J. (Medical University of South Carolina) ; Elm, Jordan J. (Medical University of South Carolina) ; Kim, Anthony S. (University of California) ; Lindblad, Anne S. (Emmes Corporation) ; Palesch, Yuyo Y. (Medical University of South Carolina) ; Zhao, Wenle (Medical University of South Carolina) ; Pauls, Keith (Medical University of South Carolina) ; Walsh, Kyle B. (University of Cincinnati) ; Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ; Bernstein, Richard A. (Northwestern University) ; Johnston, Claiborne (University of Texas at Austin) ; Universitat Autònoma de Barcelona
Debate continues about the value of event adjudication in clinical trials and whether independent centralized assessments improve reliability and validity of study results in masked randomized trials compared with local, investigator-assessed end points. [...]
2019 - 10.1001/jamanetworkopen.2019.10769
JAMA network open, Vol. 2 Núm. 9 (june 2019) , p. e1910769  

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