Home > Search Results: Fernández de Larrea, Carlos
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Articles, 4 records found
Articles 4 records found  
1.
11 p, 618.2 KB Characterization of the endotheliopathy, innate-immune activation and hemostatic imbalance underlying CAR-T cell toxicities : Laboratory tools for an early and differential diagnosis / Moreno-Castaño, Ana Belén (Hospital Clínic i Provincial de Barcelona) ; Fernández, Sara (Hospital Clínic i Provincial de Barcelona) ; Ventosa, Helena (Hospital Clínic i Provincial de Barcelona) ; Palomo, Marta (Hospital Clínic i Provincial de Barcelona) ; Martinez-Sanchez, Julia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Ramos, Alex (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Ortiz-Maldonado, Valentín (Hospital Clínic i Provincial de Barcelona) ; Delgado, Julio (Hospital Clínic i Provincial de Barcelona) ; Fernández De Larrea, Carlos (Hospital Clínic i Provincial de Barcelona) ; Urbano-Ispizua, Alvaro (Hospital Clínic i Provincial de Barcelona) ; Penack, Olaf (Charité Universitätsmedizin Berlin, Germany) ; Nicolás, J.M. (Hospital Clínic i Provincial de Barcelona) ; Téllez, Adrian (Hospital Clínic i Provincial de Barcelona) ; Escolar, Ginès (Hospital Clínic i Provincial de Barcelona) ; Carreras, Enric (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Fernández-Avilés, Francesc (Hospital Clínic i Provincial de Barcelona) ; Castro Rebollo, Pedro (Hospital Clínic i Provincial de Barcelona) ; Diaz-Ricart, Maribel (Hospital Clínic i Provincial de Barcelona)
Background Chimeric antigen receptor (CAR)-T cell-based immunotherapy constitutes a revolutionary advance for treatment of relapsed/refractory hematological malignancies. Nevertheless, cytokine release and immune effector cell-associated neurotoxicity syndromes are life-threatening toxicities in which the endothelium could be a pathophysiological substrate. [...]
2023 - 10.1136/jitc-2022-006365
Journal for immunotherapy of cancer, Vol. 11 Núm. 4 (april 2023)  
Detailed record - Creative Commons
2.
3 p, 464.4 KB The Progress Test of the European Hematology Association : A New Tool for Continuous Learning / Wondergem, Marielle J. (Amsterdam UMC. University Medical Center) ; Almeida, António (Hospital da Luz (Lisboa, Portugal)) ; Brolin, Janaki (Central Hospital Karlstad) ; Fernández de Larrea, Carlos (Hospital Clínic i Provincial de Barcelona) ; van Havre, Nathalie (European Hematology Association (EHA)) ; Hemker, Bas T. (Cito) ; Hollegien, Wietske (European Hematology Association (EHA)) ; Navarro, José-Tomás (Universitat Autònoma de Barcelona) ; Prahladan, Mahesh (University of Cambridge) ; Rovó, Alicia (Bern University Hospital) ; Birgegård, Gunnar (Uppsala Unicversity)
2022 - 10.1097/HS9.0000000000000815
HemaSphere, Vol. 6 (november 2022)  
Detailed record - Creative Commons
3.
11 p, 6.7 MB Gene Expression Analysis of the Bone Marrow Microenvironment Reveals Distinct Immunotypes in Smoldering Multiple Myeloma Associated to Progression to Symptomatic Disease / Isola, Ignacio (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Brasó-Maristany, Fara (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Moreno, David F. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Mena, Mari Pau (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Oliver-Caldés, Aina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Paré Brunet, Laia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Rodríguez Lobato, Luis Gerardo (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Martín-Antonio, B (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Cibeira, María Teresa (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Bladé Creixenti, Juan (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Rosiñol, Laura (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Prat, Aleix (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Lozano, Ester (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Fernández de Larrea, Carlos (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Background: We previously reported algorithms based on clinical parameters and plasma cell characteristics to identify patients with smoldering multiple myeloma (SMM) with higher risk of progressing who could benefit from early treatment. [...]
2021 - 10.3389/fimmu.2021.792609
Frontiers in immunology, Vol. 12 (22 2021) , p. 792609  
Detailed record - Creative Commons
4.
27 p, 3.4 MB T cells isolated from G-CSF-treated multiple myeloma patients are suitable for the generation of BCMA-directed CAR-T cells / Battram, Anthony M (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Oliver-Caldés, Aina (Hospital Clínic i Provincial de Barcelona) ; Suárez Lledó, Maria (Hospital Clínic i Provincial de Barcelona) ; Lozano, Miquel (Hospital Clínic i Provincial de Barcelona) ; Bosch i Crespo, Miquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Martínez Cibrián, Núria (Hospital Clínic i Provincial de Barcelona) ; Cid, Joan (Hospital Clínic i Provincial de Barcelona) ; Moreno, David F. (Hospital Clínic i Provincial de Barcelona) ; Rodríguez Lobato, Luis Gerardo (Hospital Clínic i Provincial de Barcelona) ; Urbano Ispizua, Álvaro (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Fernández de Larrea, Carlos (Universitat de Barcelona)
Autologous cell immunotherapy using B cell maturation antigen (BCMA)-targeted chimeric antigen receptor (CAR)-T cells is an effective novel treatment for multiple myeloma (MM). This therapy has only been used for relapsed and refractory patients, at which stage the endogenous T cells used to produce the CAR-T cells are affected by the immunosuppressive nature of advanced MM and/or side effects of previous therapies. [...]
2022 - 10.1016/j.omtm.2022.06.010
Molecular Therapy. Methods & Clinical Development, Vol. 26 (august 2022) , p. 207-223  
Detailed record - Creative Commons

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