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18 p, 4.2 MB Characterization of broadly neutralizing antibody responses to HIV-1 in a cohort of long term non-progressors / González, Nuria (Instituto de Salud Carlos III) ; McKee, Krisha (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Washington, United States of America) ; Lynch, Rebecca M. (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Washington, United States of America) ; Georgiev, Ivelin S. (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Washington, United States of America) ; Jimenez, Laura (Instituto de Salud Carlos III) ; Grau, Eulàlia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Yuste, Eloísa (Hospital Clínic i Provincial de Barcelona) ; Kwong, Peter D. (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Washington, United States of America) ; Mascola, John R. (Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, Washington, United States of America) ; Alcami, Jose (Instituto de Salud Carlos III)
Only a small fraction of HIV-1-infected patients develop broadly neutralizing antibodies (bNAbs), a process generally associated to chronic antigen stimulation. It has been described that rare aviremic HIV-1-infected patients can generate bNAbs but this issue remains controversial. [...]
2018 - 10.1371/journal.pone.0193773
PloS one, Vol. 13 (march 2018)  

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