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13 p, 2.9 MB Cell survival during complete nutrient deprivation depends on lipid droplet-fueled beta-oxidation of fatty acids / González Cabodevilla, Ainara (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Sanchez Caballero, Laura (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Nintou, Eleni (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Georgieva Boiadjieva, Violeta (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Picatoste Ramón, Fernando (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Gubern Burset, Albert (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Claro Izaguirre, Enrique (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Cells exposed to stress of different origins synthesize triacylglycerols and generate lipid droplets (LD), but the physiological relevance of this response is uncertain. Using complete nutrient deprivation of cells in culture as a simple model of stress, we have addressed whether LD biogenesis has a protective role in cells committed to die. [...]
2013 - 10.1074/jbc.M113.466656
Journal of biological chemistry, Vol. 288, Num. 39 (September 2013) , p. 27777-27788  
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