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20 p, 24.8 MB Constitutive Activation of p62/Sequestosome-1-Mediated Proteaphagy Regulates Proteolysis and Impairs Cell Death in Bortezomib-Resistant Mantle Cell Lymphoma / Quinet, Grégoire (Laboratoire de Chimie de Coordination (LCC) CNRS-UPR8241) ; Xolalpa, Wendy (CIC bioGUNE) ; Reyes Garau, Diana (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Profitós-Pelejà, Núria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Azkargorta, Mikel (CICbioGUNE) ; Ceccato, Laurie (Laboratoire de Chimie de Coordination (LCC) CNRS-UPR8241) ; Gonzalez-Santamarta, María (Laboratoire de Chimie de Coordination (LCC) CNRS-UPR8241) ; Marsal, Maria (Institut de Ciències Fotòniques) ; Andilla, Jordi (Institut de Ciències Fotòniques) ; Aillet, Fabienne (CIC bioGUNE) ; Bosch, Francesc (Vall d'Hebron Institut d'Oncologia) ; Elortza, Felix (CICbioGUNE) ; Loza-Alvarez, Pablo (Institut de Ciències Fotòniques) ; Sola, Brigitte (INSERM UMR1245. Unicaen) ; Coux, Olivier (Centre de Recherche de Biologie Cellulaire de Montpellier (CRBM) CNRS-UMR 5237. Université de Montpellier) ; Matthiesen, Rune (Computational and Experimental Biology Group. CEDOC-Chronic Diseases Research Center. Universidade Nova de Lisboa) ; Roué, Gaël (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Rodriguez, Manuel S. (Laboratoire de Chimie de Coordination (LCC) CNRS-UPR8241)
Protein ubiquitylation coordinates crucial cellular events in physiological and pathological conditions. A comparative analysis of the ubiquitin proteome from bortezomib (BTZ)-sensitive and BTZ-resistant mantle cell lymphoma (MCL) revealed an enrichment of the autophagy-lysosome system (ALS) in BTZ-resistant cells. [...]
2022 - 10.3390/cancers14040923
Cancers, Vol. 14 Núm. 4 (Feb. 2022) , art. 923  
Detailed record - Creative Commons

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