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9 p, 925.7 KB The effect of intracoronary infusion of bone marrow-derived mononuclear cells on all-cause mortality in acute myocardial infarction : the BAMI trial / Mathur, Anthony (Centre for Cardiovascular Medicine & Devices, Queen Mary University of London) ; Fernández Avilés, F. (Hospital General Universitario Gregorio Marañón) ; Bartunek, Jozef (Cardiovascular Center, OLV Hospital Aalst) ; Belmans, Ann (KU) ; Crea, Filippo (Fondazione Policlinico Universitario A. Gemelli IRCCS) ; Dowlut, Sheik (Centre for Cardiovascular Medicine & Devices, Queen Mary University of London) ; Galiñanes, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Good, Marie-Claire (Queen Mary University of London) ; Hartikainen, Juha (Kuopio University Hospital ( Finlàndia)) ; Hauskeller, Christine (University of Exeter) ; Janssens, Stefan (University Hospitals Leuven (Bèlgica)) ; Kala, Petr (University Hospital Brno (República Txeca)) ; Kastrup, Jens (University of Copenhagen) ; Martin, John (University College London) ; Menasché, Philippe (Department of Cardiovascular Surgery, Hôpital Européen Georges Pompidou and University of Paris) ; Sanz-Ruiz, Ricardo (Hospital General Universitario Gregorio Marañón) ; Ylä-Herttuala, Seppo (University of Eastern Finland) ; Zeiher, Andreas Michael (Department of Medicine III, Goethe University of Frankfurt) ; Universitat Autònoma de Barcelona
Bone marrow-derived mononuclear cell (BM-MNC) therapy may improve myocardial recovery in patients following acute myocardial infarction (AMI), though existing trial results are inconsistent. Originally an open-label, multicentre Phase III trial, BAMI was designed to demonstrate the safety and efficacy of intracoronary infusion of BM-MNCs in reducing the time to all-cause mortality in patients with reduced left ventricular ejection fraction (LVEF, ≤45%) after primary angioplasty (PPCI) for ST-elevation AMI. [...]
2020 - 10.1093/eurheartj/ehaa651
European heart journal, Vol. 41 (august 2020) , p. 3702-3710  
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