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7 p, 979.4 KB pCRP-mCRP dissociation mechanisms as potential targets for the development of small-molecule anti-inflammatory chemotherapeutics / Caprio, Vittorio (Manchester Metropolitan University) ; Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau) ; Di Napoli, Mario (Ospedale San Camillo de Lellis) ; Fang, Wen-Hui (Manchester Metropolitan University) ; Ferris, Glenn R. (Manchester Metropolitan University) ; Guo, Baoqiang (Weifang Medical University) ; Iemma, Rocco S. (Manchester Metropolitan University) ; Liu, Donghui (University of Medicine and Pharmacy) ; Zeinolabediny, Yasmin (University of Medicine and Pharmacy) ; Slevin, Mark (University of Medicine and Pharmacy) ; Universitat Autònoma de Barcelona
Circulating C-reactive protein (CRP) is a key acute-phase protein and one of the main clinical biomarkers for inflammation and infection. CRP is an important upstream mediator of inflammation and is associated with the onset of a number of important disease states including cardiovascular disease and neurodegenerative disorders such as Alzheimer's disease. [...]
2018 - 10.3389/fimmu.2018.01089
Frontiers in immunology, Vol. 9 Núm. MAY (28 2018) , p. 1089  
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