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HCV eradication with IFN-based therapy does not completely restore gene expression in PBMCs from HIV/HCV-coinfected patients
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Brochado Kith, Óscar (Instituto de Salud Carlos III) ;
Martínez, Isidoro (Instituto de Salud Carlos III) ;
Berenguer, Juan (Hospital General Universitario Gregorio Marañón) ;
Medrano, Luz María (Instituto de Salud Carlos III) ;
González-García, Juan (Hospital Universitario La Paz (Madrid)) ;
Jiménez-Sousa, María Ángeles (Instituto de Salud Carlos III) ;
Carrero, Ana (Hospital General Universitario Gregorio Marañón) ;
Hontañón Antoñana, Víctor (Hospital Universitario La Paz (Madrid)) ;
Navarro, Jordi (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Guardiola Tey, Jose Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Fernández-Rodríguez, Amanda (Instituto de Salud Carlos III) ;
Resino, Salvador (Instituto de Salud Carlos III) ;
Miralles, P. (GESIDA Study Group) ;
López, J.C. (GESIDA Study Group) ;
Parras, F. (GESIDA Study Group) ;
Padilla, B. (GESIDA Study Group) ;
Aldámiz-Echevarría, T (GESIDA Study Group) ;
Tejerina, F. (GESIDA Study Group) ;
Díez, C. (GESIDA Study Group) ;
Pérez-Latorre, L. (GESIDA Study Group) ;
Fanciulli, C. (GESIDA Study Group) ;
Gutiérrez, I. (GESIDA Study Group) ;
Ramírez, M. (GESIDA Study Group) ;
Carretero, S. (GESIDA Study Group) ;
Bellón, José-María (GESIDA Study Group) ;
Bermejo, Javier (GESIDA Study Group) ;
Arribas, Jose (GESIDA Study Group) ;
Montes, M.L. (GESIDA Study Group) ;
Bernardino, I. (GESIDA Study Group) ;
Pascual, J.F. (GESIDA Study Group) ;
Zamora, Francisco (GESIDA Study Group) ;
Peña, J.M. (GESIDA Study Group) ;
Arnalich, F. (GESIDA Study Group) ;
Díaz, M. (GESIDA Study Group) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Van den Eynde, E. (Hospital Universitari Vall d'Hebron) ;
Pérez, M. (GESIDA Study Group) ;
Ribera, E. (Hospital Universitari Vall d'Hebron) ;
Crespo Casal, Manuel (Hospital Universitari Vall d'Hebron) ;
Casado, José Luis (GESIDA Study Group) ;
Dronda, F. (GESIDA Study Group) ;
Moreno, A. (GESIDA Study Group) ;
Pérez-Elías, M.J. (GESIDA Study Group) ;
Sanfrutos, M.A. (GESIDA Study Group) ;
Moreno, S. (GESIDA Study Group) ;
Quereda, C. (GESIDA Study Group) ;
Arranz, A. (GESIDA Study Group) ;
Casas, E. (GESIDA Study Group) ;
de Miguel, J. (GESIDA Study Group) ;
Schroeder, S. (GESIDA Study Group) ;
Sanz, J. (GESIDA Study Group) ;
Santos, I. (GESIDA Study Group) ;
Bustinduy, M.J. (GESIDA Study Group) ;
Iribarren, J.A. (GESIDA Study Group) ;
Rodríguez-Arrondo, F. (GESIDA Study Group) ;
Von-Wichmann, M.A. (GESIDA Study Group) ;
Vergas, J. (GESIDA Study Group) ;
Téllez, M.J. (GESIDA Study Group) ;
Vinuesa, D. (GESIDA Study Group) ;
Muñoz, L. (GESIDA Study Group) ;
Hernández-Quero, J. (GESIDA Study Group) ;
Ferrer, A. (GESIDA Study Group) ;
Galindo, María José (GESIDA Study Group) ;
Ortiz, L. (GESIDA Study Group) ;
Ortega, E. (GESIDA Study Group) ;
Montero, M. (GESIDA Study Group) ;
Blanes, M. (GESIDA Study Group) ;
Cuellar, S. (GESIDA Study Group) ;
Lacruz, J. (GESIDA Study Group) ;
Salavert, M. (GESIDA Study Group) ;
López-Aldeguer, J. (GESIDA Study Group) ;
Pérez, G. (GESIDA Study Group) ;
Gaspar, G. (GESIDA Study Group) ;
Yllescas, M. (GESIDA Study Group) ;
Crespo, P. (GESIDA Study Group) ;
Aznar, E. (GESIDA Study Group) ;
Esteban, H. (GESIDA Study Group)
Objective: To evaluate the impact of hepatitis C virus (HCV) elimination via interferon (IFN)-based therapy on gene expression profiles related to the immune system in HIV/HCV-coinfected patients. Methods: We conducted a prospective study in 28 HIV/HCV-coinfected patients receiving IFN-based therapy at baseline (HIV/HCV-b) and week 24 after sustained virological response (HIV/HCV-f). [...]
2021 -  10.1186/s12929-021-00718-6
Journal of Biomedical Science, Vol. 28 Núm. 1 (december 2021) , p. 23
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