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Artículos, Encontrados 4 registros
Artículos Encontrados 4 registros  
1.
8 p, 533.2 KB Rationale and methodology for a European pooled analysis of postmarketing interventional and observational studies of insulin glargine 300 U/mL in diabetes : Protocol of REALI project / Freemantle, N. (University College London) ; Bonadonna, Riccardo C (University of Parma) ; Gourdy, P. (Paul Sabatier University) ; Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ; Mueller-Wieland, D. (University Hospital Aachen (Alemanya)) ; Bigot, Gregory (IVIDATA) ; Ciocca, A. (Sanofi SA) ; Mauquoi, C. (IDDI SA) ; Rollot, M. (Quinten) ; Bonnemaire, Mireille (Sanofi SA) ; Universitat Autònoma de Barcelona
Type 2 diabetes mellitus (T2DM) is a common and heterogeneous disease. Using advanced analytic approaches to explore real-world data may identify different disease characteristics, responses to treatment and progression patterns. [...]
2020 - 10.1136/bmjopen-2019-033659
BMJ open, Vol. 10 Núm. 4 (28 2020) , p. 201903365  
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2.
17 p, 389.2 KB Does Gender Influence the Effectiveness and Safety of Insulin Glargine 300 U/ml in Patients with Uncontrolled Type 2 Diabetes? Results from the REALI European Pooled Analysis / Gourdy, Pierre (Université de Toulouse) ; Bonadonna, Riccardo C. (University of Parma) ; Freemantle, Nick (University College London) ; Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ; Müller-Wieland, Dirk (University Hospital Aachen (Alemanya)) ; Bigot, Gregory (IVIDATA) ; Mauquoi, Celine (IDDI) ; Ciocca, Alice (General Medicines. Sanofi) ; Bonnemaire, Mireille (General Medicines. Sanofi)
Introduction: Gender differences in risk factors and treatment outcomes for type 2 diabetes mellitus (T2DM) may exist. We used the REALI European database to investigate whether there were gender-specific differences in baseline characteristics and clinical outcomes among patients with inadequately controlled T2DM initiated on insulin glargine 300 U/ml (Gla-300). [...]
2022 - 10.1007/s13300-021-01179-8
Diabetes Therapy, Vol. 13 Núm. 1 (january 2022) , p. 57-73  
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3.
25 p, 618.2 KB Impact of Age on the Effectiveness and Safety of Insulin Glargine 300 U/mL : Results from the REALI European Pooled Data Analysis / Bonadonna, Riccardo C (University of Parma) ; Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ; Müller-Wieland, Dirk (University Hospital Aachen (Alemanya)) ; Freemantle, Nick (University College London) ; Bigot, Gregory (IVIDATA Group) ; Mauquoi, Celine (International Drug Development Institute (IDDI)) ; Ciocca, Alice (Sanofi) ; Bonnemaire, Mireille (Sanofi) ; Gourdy, Pierre (Université de Toulouse)
Introduction: Patients aged ≥ 65 years continue to be underrepresented in clinical studies related to type 2 diabetes mellitus (T2DM). Accordingly, the REALI pooled analysis was performed to evaluate the effectiveness and safety of insulin glargine 300 U/mL (Gla-300) across different age subgroups, using data from 14 interventional and non-interventional studies. [...]
2021 - 10.1007/s13300-021-01030-0
Diabetes Therapy, Vol. 12 Núm. 4 (april 2021) , p. 1073-1097  
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4.
16 p, 628.4 KB Glycaemic Control with Insulin Glargine 300 U/mL in Individuals with Type 2 Diabetes and Chronic Kidney Disease : A REALI European Pooled Data Analysis / Mauricio Puente, Dídac (Institut d'Investigació Biomèdica Sant Pau) ; Gourdy, P. (Institute of Metabolic and Cardiovascular Diseases. UMR1048 INSERM/UPS. Toulouse University) ; Bonadonna, Riccardo C (Department of Medicine and Surgery. University of Parma) ; Freemantle, N. (Institute of Clinical Trials and Methodology. University College London) ; Bigot, Gregory (IVIDATA) ; Mauquoi, C. (IDDI) ; Ciocca, A. (General Medicines. Sanofi) ; Bonnemaire, Mireille (General Medicines. Sanofi) ; Müller-Wieland, D. (Department of Medicine I. University Hospital Aachen)
Introduction: Management of type 2 diabetes mellitus (T2DM) in patients with chronic kidney disease is complex. Using the REALI European pooled database, we determined the impact of baseline renal function on the effectiveness and safety of insulin glargine 300 U/mL (Gla-300) initiated in adults with inadequately controlled T2DM. [...]
2021 - 10.1007/s13300-021-01031-z
Diabetes Therapy, Vol. 12 Núm. 4 (april 2021) , p. 1159-1174  
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