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Artículos, Encontrados 6 registros
Artículos Encontrados 6 registros  
1.
11 p, 1.9 MB Many people with chronic lymphocytic leukemia or small lymphocytic lymphoma benefit from ibrutinib treatment up to 8 years : a plain language summary / Barr, Paul M. (University of Rochester Medical Center, USA) ; Owen, Carolyn (University of Calgary, Canada) ; Robak, Tadeusz (Medical University of Lodz, Copernicus Memorial Hospital, Lodz, Poland) ; Tedeschi, Alessandra (ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy) ; Bairey, Osnat (Rabin Medical Center, Petah Tikva, Israel) ; Burger, Jan A (University of Texas MD Anderson Cancer Center, Houston, USA) ; Hillmen, Peter (The Leeds Teaching Hospitals, St James Institute of Oncology, Leeds, UK) ; Dearden, Claire (The Royal Marsden Hospital, London, UK) ; Grosicki, Sebastian (Silesian Medical University, Katowice, Poland) ; McCarthy, Helen (Royal Bournemouth General Hospital (Dorset, Regne Unit)) ; Li, Jian Yong (Jiangsu Province Hospital, Nanjing, China) ; Offner, Fritz (Universitair Ziekenhuis Gent, Belgium) ; Moreno, Carol (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Jermain, Mandy (Pharmacyclics LLC, an AbbVie Company, South San Francisco, USA) ; Zhou, Cathy (Pharmacyclics LLC, an AbbVie Company, South San Francisco, USA) ; Hsu, Emily (Pharmacyclics LLC, an AbbVie Company, South San Francisco, USA) ; Szoke, Anita (Pharmacyclics LLC, an AbbVie Company, South San Francisco, USA) ; Kipps, Thomas J. (UCSD Moores Cancer Center, San Diego, USA) ; Ghia, Paolo (Università Vita-Salute San Raffaele &IRCCS Ospedale San Raffaele, Milan, Italy)
What is this summary about? This is a plain language summary of a publication describing long-term results from the RESONATE-2 study with up to 8 years of follow-up. The original paper was published in Blood Advances in June 2022. [...]
2022 - 10.2217/fon-2022-0898
Future oncology (London, England), Vol. 18 Núm. 37 (january 2022)  
2.
9 p, 996.2 KB Sustained efficacy and detailed clinical follow-up of first-line ibrutinib treatment in older patients with chronic lymphocytic leukemia : Extended phase 3 results from RESONATE-2 / Barr, Paul M. (University of Rochester) ; Robak, Tadeusz (Medical University of Lodz) ; Owen, Carolyn (Tom Baker Cancer Centre) ; Tedeschi, Alessandra (ASST Grande Ospedale Metropolitano Niguarda) ; Bairey, Osnat (Sackler Faculty of Medicine. Tel Aviv University) ; Bartlett, Nancy L. (Washington University School of Medicine) ; Burger, Jan A. (University of Texas MD Anderson Cancer Center) ; Hillmen, Peter (The Leeds Teaching Hospitals. St. James Institute of Oncology) ; Coutre, Steven E (Stanford University School of Medicine) ; Devereux, Stephen (Kings College Hospital) ; Grosicki, Sebastian (School of Public Health. Silesian Medical University) ; McCarthy, Helen (Royal Bournemouth Hospital) ; Li, Jianyong (Jiangsu Province Hospital) ; Simpson, David (North Shore Hospital) ; Offner, Fritz (Universitair Ziekenhuis Gent) ; Moreno, Carol (Institut d'Investigació Biomèdica Sant Pau) ; Zhou, Cathy (Pharmacyclics. LLC an AbbVie Company) ; Styles, Lori (Pharmacyclics. LLC an AbbVie Company) ; James, Danelle (Pharmacyclics. LLC an AbbVie Company) ; Kipps, Thomas J (University of California,San Diego. Moores Cancer Center) ; Ghia, Paolo (Università Vita-Salute San Raffaele and IRCCS Istituto Scientifico San Raffaele) ; Universitat Autònoma de Barcelona
Results of RESONATE-2 (PCYC-1115/1116) supported approval of ibrutinib for first-line treatment of chronic lymphocytic Rleukemia. Extended analysis of RESONATE-2 was conducted to determine long-term efficacy and safety of ibrutinib in older patients with chronic lymphocytic leukemia. [...]
2018 - 10.3324/haematol.2018.192328
Haematologica, Vol. 103 Núm. 9 (31 2018) , p. 1502-1510  
3.
9 p, 1.3 MB Single-agent ibrutinib versus chemoimmunotherapy regimens for treatment-naïve patients with chronic lymphocytic leukemia : A cross-trial comparison of phase 3 studies / Robak, Tadeusz (Medical University of Lodz) ; Burger, Jan A. (The University of Texas MD Anderson Cancer Center) ; Tedeschi, Alessandra (ASST Grande Ospedale Metropolitano Niguarda) ; Barr, Paul M. (University of Rochester Cancer Center) ; Owen, Carolyn (University of Calgary) ; Bairey, Osnat (Tel Aviv University) ; Hillmen, Peter (St. James's Institute of Oncology) ; Simpson, David (North Shore Hospital) ; Grosicki, Sebastian (Silesian Medical University) ; Devereux, Stephen (King's College Hospital NHS Foundation Trust) ; McCarthy, Helen (Royal Bournemouth Hospital) ; Coutre, Steven E (Stanford University School of Medicine) ; Quach, Hang (St. Vincent's Hospital) ; Gaidano, Gianluca (Amedeo Avogadro University of Eastern Piedmont) ; Maslyak, Zvenyslava (Institute of Blood Pathology and Transfusion Medicine of the Academy of Medical Sciences of Ukraine) ; Stevens, Don A. (Norton Cancer Institute) ; Moreno, Carol (Institut d'Investigació Biomèdica Sant Pau) ; Gill, Devinder S. (Princess Alexandra Hospital) ; Flinn, Ian W. (Sarah Cannon Research Institute/Tennessee Oncology) ; Gribben, John G. (Queen Mary University of London) ; Mokatrin, Ahmad (Pharmacyclics LLC. an AbbVie Company) ; Cheng, Mei (Pharmacyclics LLC. an AbbVie Company) ; Styles, Lori (Pharmacyclics LLC. an AbbVie Company) ; James, Danelle F. (Pharmacyclics LLC. an AbbVie Company) ; Kipps, Thomas J (University of California San Diego) ; Ghia, Paolo (Università Vita-Salute San Raffaele and IRCCS Istituto Scientifico San Raffaele) ; Universitat Autònoma de Barcelona
Chemoimmunotherapy (CIT) and targeted therapy with single-agent ibrutinib are both recommended first-line treatments for chronic lymphocytic leukemia (CLL), although their outcomes have not been directly compared. [...]
2018 - 10.1002/ajh.25259
American Journal of Hematology, Vol. 93 Núm. 11 (november 2018) , p. 1402-1410  
4.
11 p, 1.4 MB Reproducibility in the absence of selective reporting : An illustration from large-scale brain asymmetry research / Kong, Xiang-Zhen (Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, Netherlands) ; Francks, Clyde (Donders Institute for Brain, Cognition and Behaviour, Radboud University) ; Mathias, Samuel R. ; Guadalupe, Tulio ; Abé, Christoph ; Agartz, Ingrid ; Akudjedu, Theophilus (Bournemouth University) ; Aleman, André ; Alhusaini, Saud ; Allen, Nicholas B. ; Ames, David ; Andreassen, Ole A ; Vasquez, A.A. ; Armstrong, Nicola (Curtin University (Perth, Australia)) ; Asherson, P. ; Bergo, F. ; Bastin, Mark E ; Batalla, A. ; Bauer, Jochen (Westfälische Wilhelms-Universität Münste) ; Baune, B.T. ; Baur-Streubel, Ramona ; Biederman, J. ; Blaine, S.K. ; Boedhoe, Premika (location VUmc) ; Bøen, Erlend ; Bose, Anushree (National Institute of Mental Health and Neurosciences) ; Bralten, J. ; Brandeis, Daniel (Medizinische Fakultät Mannheim) ; Brem, Silvia (Psychiatrische Universitätsklinik Zürich) ; Brodaty, Henry ; Yüksel, Dilara (SRI International (Menlo Park, California)) ; Brooks, S.J. ; Buitelaar, Jan K. (Donders Institute for Brain, Cognition and Behaviour, Netherlands) ; Bürger, C. ; Bülow, R. ; Calhoun, Vince ; Calvo, A. ; Canales-Rodriguez, Erick Jorge ; Cannon, Dara (University of Galway) ; Caparelli, E.C. ; Castellanos, F.X. ; Cendes, Fernando (Universidade Estadual de Campinas (Brasil)) ; Chaim-Avancini, T.M. ; Chantiluke, K. ; Chen, Qunlin (Southwest University (Chongqing, Xina)) ; Chen, X. ; Cheng, Y. ; Christakou, Anastasia (Centre for Integrate Neuroscience and Neurodynamics) ; Clark, Vincent P. (University of New Mexico) ; Coghill, David ; Connolly, C.G. ; Conzelmann, A. ; Córdova-Palomera, A. ; Cousijn, Janna (Universiteit van Amsterdam) ; Crow, T. ; Cubillo, A. ; Dannlowski, Udo ; de Bruttopilo, S.A. ; de Zeeuw, P. ; Deary, I.J. ; Demeter, D.V. ; Di Martino, A. ; Dickie, E.W. ; Dietsche, B. ; Doan, N.T. ; Doherty, Colin P. (Trinity College Dublin) ; Doyle, A. ; Durston, S. ; Earl, Eric ; Ehrlich, Stefan (University Hospital C.G. Carus) ; Ekman, Carl Johan (Norra Stockholms psykiatri) ; Elvsåshagen, T. ; Epstein, J.N. ; Fair, D.A. ; Faraone, S.V. ; Fernández, G. ; Flint, C. ; Filho, G.B. ; Förster, K. ; Fouche, J.P. ; Foxe, J.J. ; Frodl, T. ; Fuentes-Claramonte, Paola (FIDMAG Germanes Hospitalàries Research Foundation (Barcelona, Catalunya)) ; Fullerton, Janice M. (Neuroscience Research Australia) ; Garavan, H. ; do Santos Garcia, D. ; Gotlib, I.H. ; Goudriaan, A.E. ; Grabe, H.J. ; Groenewold, Nynke A. ; Grotegerd, D. ; Gruber, O. ; Gurholt, Tiril Pedersen (Oslo University Hospital (Oslo, Noruega)) ; Haavik, J. ; Hahn, T. ; Hansell, Narelle K. (University of Queensland) ; Harris, M.A. ; Hartman, C.A. ; del Carmen Valdés Hernández, M. ; Heslenfeld, D. ; Hester, R. ; Hibar, Derrek Paul (Genentech, Inc) ; Ho, Beng-Choon (University of Iowa Carver College of Medicine) ; Ho, T.C. ; Hoekstra, P.J. ; van Holst, R.J. ; Hoogman, Martin (Donders Institute for Brain, Cognition and Behaviour (The Netherlands)) ; Høvik, M.F. ; Howells, F.M. ; Hugdahl, K. ; Huyser, Chaim (Amsterdam UMC) ; Ingvar, M. ; Ishikawa, A. ; James, A. ; Jahanshad, Neda (Keck School of Medicine of USC) ; Jernigan, T.L. ; Jönsson, Erik G. (University of Oslo) ; Kaleda, V. ; Kelly, Clare (Trinity College Dublin) ; Kerich, M. ; Keshavan, M.S. ; Khadka, S. ; Kircher, Tilo (Philipps-Universität Marburg) ; Kohls, G. ; Konrad, K. ; Korucuoglu, O. ; Krämer, B. ; Krug, A. ; Kuntsi, J. ; Kwon, J.S. ; Lambregts-Rommelse, N. ; Landén, M. ; Lázaro, Luisa (Hospital Clínic i Provincial de Barcelona) ; Lebedeva, Irina S ; Lenroot, R. ; Lesch, K.P. ; Li, Q. ; Lim, Kelvin (University of Minnesota) ; Liu, J. ; Lochner, C. ; London, E.D. ; Lorenzetti, V. ; Luciano, M. ; Luijten, M. ; Lundervold, A.J. ; Mackey, S. ; MacMaster, Frank (University of Calgary Cumming School of Medicine) ; Maingault, S. ; Malpas, Charles B. (Royal Melbourne Hospital (Melbourne, Austràlia)) ; Malt, U.F. ; Mataix-Cols, D. ; Martin-Santos, R. ; Mayer, A.R. ; McCarthy, H. ; Medland, Sarah E. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ; Metha, M. ; Mitchell, P.B. ; Mueller, B.A. ; Maniega, S.M. ; Mazoyer, Bernard (Institut des Maladies Neurodégénératives) ; McDonald, Colm (University of Galway) ; McLellan, Quinn (University of Alberta) ; McMahon, Katie (Queensland University of Technology) ; McPhilemy, Genevieve (University of Galway) ; Momenan, Reza (National Institutes of Health NIH) ; Morales, Angelica M. (OHSU School of Medicine) ; Narayanaswamy, Janardhanan C. ; Moreira, José Carlos Vasques ; Nerland, Stener ; Nestor, Liam ; Newman, E. ; Nigg, J.T. ; Nordvik, J.E. ; Novotny, S. ; Weiss, E.O. ; O'Gorman, R.L. ; Oosterlaan, J. ; Oranje, B. ; Orr, C. ; Overs, B. ; Paloyelis, Y. ; Pauli, P. ; Paulus, M. ; Plessen, K.J. ; von Polier, G.G. ; Pomarol-Clotet, E. ; Portella, Maria J.. (Institut d'Investigació Biomèdica Sant Pau) ; Qiu, J. ; Radua, Joaquim (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Ramos-Quiroga, J.A. ; Reddy, Y.C.J. ; Reif, A. ; Roberts, G. ; Rosa, P. ; Rubia, K. ; Sacchet, M.D. ; Sachdev, P.S. ; Salvador, R. ; Schmaal, L. ; Schulte-Rüther, Martin (University Medical Center Göttingen) ; Schweren, L. ; Seitz, J. ; Serpa, Mauricio (King's College London) ; Shaw, P. ; Shumskaya, E. ; Silk, Tim (Deakin University (Melbourne, Australia)) ; Simmons, A.N. ; Simulionyte, E. ; Sinha, R. ; Sjoerds, Z. ; Smelror, R.E. ; Soliva, J.C. ; Solowij, N. ; Souza-Duran, Fabio Luis (Universidade de São Paulo) ; Sponheim, S.R. ; Stein, Dan J. (University of Cape Town) ; Stein, E.A. ; Stevens, M. ; Strike, Lachlan (University of Queensland) ; Sudre, G. ; Sui, Jing ; Tamm, L. ; Temmingh, H.S. ; Thoma, R.J. ; Tomyshev, A. ; Tronchin, Giulia ; Turner, Jessica ; Uhlmann, Anne (TU Dresden) ; van Erp, Theo G. M. ; van den Heuvel, Odile A. (Haukeland University Hospital (Bergen, Noruega)) ; van der Meer, Dennis (Maastricht University) ; van Eijk, Liza ; Vance, Alasdair (University of Melbourne) ; Veer, Ilya M. ; Veltman, Dick J. ; Venkatasubramanian, Ganesan (National Institute of Mental Health and Neurosciences (Bangalore, India)) ; Vilarroya Oliver, Óscar (Universitat Autònoma de Barcelona) ; Vives-Gilabert, Yolanda (Universitat de València) ; Voineskos, Aristotle (Centre for Addiction and Mental Health (Toronto, Canada)) ; Völzke, Henry (University Medicine Greifswald) ; Vuletic, Daniella (SA MRC Unit on Risk and Resilience in Mental Disorders) ; Walitza, Susanne (University of Zurich and University Hospital of Psychiatry Zurich) ; Walter, Henrik (Charité - Universitätsmedizin Berlin) ; Walton, Esther (University of Bath) ; Wardlaw, Joanna (University of Edinburgh Edinburgh Neuroscience) ; Wen, Wei (UNSW Sydney) ; Westlye, Lars T. (University of Oslo) ; Whelan, Christopher D. (Biogen) ; White, Tonya (Erasmus MC Sophia Children's Hospital) ; Wiers, Reinout (University of Amsterdam) ; Wright, Margaret J (The University of Queensland) ; Wittfeld, Katharina (Universitätsmedizin Greifswald) ; Yang, Tony T. (University of California, San Francisco) ; Yasuda, Clarissa Lin (Universidade Estadual de Campinas (Brasil)) ; Yoncheva, Yuliya N. (NYU Grossman School of Medicine) ; Yücel, Murat (Monash University) ; Yun, Je-Yeon (Seoul National University College of Medicine) ; Zanetti, Marcus Vinicius (Hospital Sirio-Libanês) ; Zhen, Zonglei (Beijing Normal University) ; Zhu, Xing-Xing (Ministry of Education of the People's Republic of China) ; Ziegler, Georg C. (University Hospital of Würzburg) ; de Zubicaray, Greig (Queensland University of Technology) ; Zwiers, Marcel P (Donders Institute for Brain, Cognition and Behaviour (The Netherlands)) ; Glahn, David C. (Children's Hospital Boston) ; Crivello, Fabrice (Institut des Maladies Neurodégénératives) ; Fisher, Simon E. (Donders Institute for Brain, Cognition and Behaviour (The Netherlands)) ; Thompson, Paul M. (Keck School of Medicine of USC) ; Farde, Lars (Karolinska Institutet (Estocolm, Suècia)) ; Flyckt, Lena (Karolinska Institutet (Estocolm, Suècia)) ; Engberg, Goran (Karolinska Institutet (Estocolm, Suècia)) ; Erhardt, Sophie (Karolinska Institutet (Estocolm, Suècia)) ; Fatouros-Bergman, Helena (Karolinska Institutet (Estocolm, Suècia)) ; Cervenka, Simon (Karolinska Institutet (Estocolm, Suècia)) ; Schwieler, Lilly (Karolinska Institutet (Estocolm, Suècia)) ; Piehl, Fredrik (Karolinska Institutet (Estocolm, Suècia)) ; Agartz, Ingrid (Karolinska Institutet (Estocolm, Suècia)) ; Collste, Karin (Karolinska Institutet (Estocolm, Suècia)) ; Victorsson, Pauliina (Region Stockholm) ; Malmqvist, Anna (Karolinska Institutet (Estocolm, Suècia)) ; Hedberg, Mikael (Karolinska Institutet (Estocolm, Suècia)) ; Orhan, Funda (Karolinska Institutet (Estocolm, Suècia)) ; Sellgren, Carl (Karolinska Institutet (Estocolm, Suècia)) ; Karolinska Schizophrenia Project
The problem of poor reproducibility of scientific findings has received much attention over recent years, in a variety of fields including psychology and neuroscience. The problem has been partly attributed to publication bias and unwanted practices such as p-hacking. [...]
2022 - 10.1002/hbm.25154
Human brain mapping, Vol. 43 Núm. 1 (january 2022) , p. 244-254  
5.
11 p, 1.4 MB Up to 8-year follow-up from RESONATE-2 : first-line ibrutinib treatment for patients with chronic lymphocytic leukemia / Barr, Paul M. (Clinical Trials Office. Wilmot Cancer Institute. University of Rochester Medical Center) ; Owen, Carolyn (Division of Hematology & Hematological Malignancies. Tom Baker Cancer Centre. University of Calgary) ; Robak, Tadeusz (Medical University of Lodz) ; Tedeschi, Alessandra (Department of Hematology. Azienda Socio Sanitaria Territoriali Grande Ospedale Metropolitano Niguarda) ; Bairey, Osnat (Department of Hematology. Rabin Medical Center) ; Burger, Jan A (Department of Leukemia. University of Texas MD Anderson Cancer Center) ; Hillmen, Peter (Department of Haematology. The Leeds Teaching Hospitals. St. James Institute of Oncology) ; Coutre, Steven E. (Stanford University School of Medicine. Stanford Cancer Cente) ; Dearden, Claire (Haemato-Oncology Department. The Royal Marsden Hospital) ; Grosicki, Sebastian (Department of Hematology and Cancer Prevention. School of Public Health. Silesian Medical University) ; McCarthy, Helen (Royal Bournemouth General Hospital. Haematology Department) ; Li, Jian-Yong (Jiangsu Province Hospital. Department of Hematology) ; Offner, Fritz (Universitair Ziekenhuis Gent. Department of Clinical Hematology) ; Moreno, Carol (Institut d'Investigació Biomèdica Sant Pau) ; Zhou, Ccathy (Biostatistics. Pharmacyclics LLC. An AbbVie Company) ; Hsu, Emily (Clinical Sciences. Pharmacyclics LLC. An AbbVie Company) ; Szoke, Anita (Clinical Sciences. Pharmacyclics LLC. An AbbVie Company) ; Kipps, Thomas J. (University of California San Diego. Department of Medicine. Moores Cancer Center) ; Ghia, Paolo (Università Vita-Salute San Raffaele. Department of Onco-Hematology. Istituto di Ricovero e Cura a Carattere Scientifico Ospedale San Raffaele) ; Universitat Autònoma de Barcelona
2022 - 10.1182/bloodadvances.2021006434
Blood advances, Vol. 6 Núm. 11 (june 2022) , p. 3440-3450  
6.
12 p, 1.8 MB Long-term efficacy and safety of first-line ibrutinib treatment for patients with CLL/SLL : 5 years of follow-up from the phase 3 RESONATE-2 study / Burger, Jan A. (University of Texas MD Anderson Cancer Center. Department of Leukemia) ; Barr, Paul M. (Wilmot Cancer Institute, University of Rochester Medical Center) ; Robak, Tadeusz (Medical University of Lodz, Copernicus Memorial Hospital) ; Owen, Carolyn (University of Calgary. Tom Baker Cancer Centre) ; Ghia, Paolo (Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele) ; Tedeschi, Alessandra (ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy) ; Bairey, Osnat (Tel Aviv University. Rabin Medical Center, Petah Tikva, Israel and Sackler Faculty of Medicine) ; Hillmen, Peter (University of Leeds. The Leeds Teaching Hospitals, St. James Institute of Oncology) ; Coutre, Steven E. (Stanford University School of Medicine. Stanford Cancer Center) ; Devereux, Stephen (NHS Foundation Trust. Kings College Hospital) ; Grosicki, Sebastian (Silesiam Medical University. Department of Hematology and Cancer Prevention) ; McCarthy, Helen (Royal Bournemouth General Hospital (Dorset, Regne Unit)) ; Simpson, David (North Shore Hospital) ; Offner, Fritz (Universitair Ziekenhuis Gent) ; Moreno, Carol (Institut d'Investigació Biomèdica Sant Pau) ; Dai, Sandra (Pharmacyclics LLC, an AbbVie Company) ; Lal, Indu (Pharmacyclics LLC, an AbbVie Company) ; Dean, James P. (Pharmacyclics LLC, an AbbVie Company) ; Kipps, Thomas J. (UCSD Moores Cancer Center) ; Universitat Autònoma de Barcelona
RESONATE-2 is a phase 3 study of first-line ibrutinib versus chlorambucil in chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL). Patients aged ≥65 years (n = 269) were randomized 1:1 to once-daily ibrutinib 420 mg continuously or chlorambucil 0. [...]
2019 - 10.1038/s41375-019-0602-x
Leukemia, Vol. 34 (october 2019) , p. 787-798  

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