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18 p, 8.2 MB SMAD4 maintains the fluid shear stress set point to protect against arterial-venous malformations / Banerjee, Kuheli (Heidelberg University) ; Lin, Yanzhu (EHeidelberg University) ; Gahn, Johannes (Heidelberg University) ; Cordero, Julio (German Centre for Cardiovascular Research) ; Gupta, Purnima (Heidelberg University) ; Mohamed, Islam (Heidelberg University) ; Graupera, Mariona (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Dobreva, Gergana (German Centre for Cardiovascular Research) ; Schwartz, Martin A. (Yale School of Medicine) ; Ola, Roxana (Heidelberg University)
Vascular networks form, remodel, and mature under the influence of both fluid shear stress (FSS) and soluble factors. Physiological FSS promotes and maintains vascular stability via synergy with bone morphogenic proteins 9 and 10 (BMP9 and BMP10). [...]
2023 - 10.1172/JCI168352
The journal of clinical investigation, Vol. 133 Núm. 18 (15 2023) , p. e168352  
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2 Mohamed, Iman Elmahdi
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