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21 p, 2.8 MB Involvement of the PI3K/AKT Intracellular Signaling Pathway in the AntiCancer Activity of Hydroxytyrosol, a Polyphenol from Olea europaea, in Hematological Cells and Implication of HSP60 Levels in Its Anti-Inflammatory Activity / Parra-Perez, Alberto M. (GENYO. Centre for Genomics and Oncological Research: Pfizer. Universidad de Granada) ; Pérez-Jiménez, Amalia (Universidad de Granada. Departamento de Zoología. Facultad de Ciencias) ; Gris-Cárdenas, Isabel (CIC bioGUNE. Centre for Cooperative Research in Biosciences) ; Bonel-Pérez, Gloria C. (Centro Nacional de Investigaciones Oncológicas Carlos III (Espanya)) ; Carrasco-Díaz, Luis Miguel (Institut d'Investigació Biomèdica Sant Pau) ; Mokhtari, khalida (Mohammed I University. Laboratory of Bioresources. Biotechnologies. Ethnopharmacology and Health. Department of Biology. Faculty of Sciences) ; García-Salguero, Encarnacion Leticia (Universidad de Granada. Departamento de Bioquímica y Biología Molecular I) ; Lupiáñez, José Antonio (Universidad de Granada. Departamento de Bioquímica y Biología Molecular I) ; Rufino-Palomares, Eva E. (Universidad de Granada. Departamento de Bioquímica y Biología Molecular I) ; Universitat Autònoma de Barcelona
Hydroxytyrosol (HT), the main representative of polyphenols of olive oil, has been described as one of the most powerful natural antioxidants, also showing anti-inflammatory, antimicrobial, cardioprotective and anticancer activity in different type of cancers, but has been little studied in hematological neoplasms. [...]
2022 - 10.3390/ijms23137053
International journal of molecular sciences, Vol. 23 Núm. 13 (july 2022) , p. 7053  

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